Administrative Core

管理（Admin）共享资源核心（SRC）的主要目标是提供基础 对AMPLIFI的所有组成部分进行整合、协调和管理，（即，三个研究项目 和三个额外的SRC）。行政SRC还负责所有预算和监管活动 （处理激励措施、IRB批准和修订、协调DSMB监督等）所需工作 所有程序组件。此外，管理SRC团队将安排会议， 调查员，并进行大部分的供应品运输，以及提交进度报告。的一部分 管理SRC将为任何研究参与者提供平板电脑和互联网服务 通过电脑、智能手机或其他设备访问互联网的人; SRC还将为需要这种支持以充分参与的参与者提供培训和指导 在三个项目中。该SRC还将维护研究免费电话号码，并将跟踪、分类和报告任何 不良事件，并将协调年度DSMB审查。 具体目标是：（1）将总体方案目标与具体项目成果相结合;（2） 协调研究项目和资源核心的活动，以确保AMPLIFI的目标和 （3）领导对AMPLIFI各组成部分的有效管理和科学整合。 我们将采用综合方法，利用共享资源核心和基础架构来实现 以下内容：1）确定如何最好地接触服务不足的老年人，农村和少数民族癌症幸存者; 2）参与 幸存者锻炼更多，选择更健康的食物，从而改善饮食质量和体重 控制; 3）确定是否应按顺序介绍特定领域的行为干预措施， 同时在这个人群中;并评估适应健康行为的成本效益 干预措施。因此，拟议的工作是跨多个层面的综合和协同作用， 研究基础设施、合作关系和研究人员的专业知识， 结果与不同部分的总和相比。

The primary objective of the Administrative (Admin) Shared Resource Core (SRC) is to provide the foundation for integration, coordination, and management of all components of AMPLIFI, (i.e., the three research projects and three additional SRCs). The Admin SRC also is responsible for all budgetary and regulatory activities (processing incentives, IRB clearance and amendments, coordinating DSMB oversight, etc.) and work required for all program components. In addition, the Admin SRC team will arrange for meetings amongst the investigators, and perform the majority of supply shipment, as well as file progress reports. As part of the supplies, the Admin SRC will provide computer tablets and internet service coverage to any study participants who do have current internet access via computers, smartphones or other devices; the IT specialist within this SRC also will provide training and guidance for participants who require this support in order to participate fully in the 3 projects. This SRC also will maintain the study toll-free number and will track, triage, and report any adverse events, and also will coordinate annual DSMB reviews. The Specific Aims are to: (1) Integrate overarching program aims with project-specific outcomes; (2) Coordinate the activities of the research projects and resource cores to ensure that the AMPLIFI goals and outcomes are achieved; and (3) Lead effective management and scientific integration of AMPLIFI components. Using a comprehensive approach, we will leverage our shared resource cores and infrastructure to accomplish the following: 1) identify how best to reach underserved older, rural, and minority cancer survivors; 2) engage survivors in exercising more and making healthier food choices that result in improved diet quality and weight control; 3) determine whether behavioral interventions in specific domains should be presented sequentially or simultaneously in this population; and assess the cost-effectiveness of the adapted health behavior interventions. Thus, the proposed work is integrated and synergistic across multiple dimensions to leverage research infrastructure, collaborative relationships, and the investigators' expertise to achieve greater outcomes compared to the sum of the differential parts.