Data Analysis Core
Data Analysis Core
批准号:
10259783
负责人:
James Paul Carson
金额:
$17.5万
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-09-10 至 2024-08-31
关键词:
3-DimensionalAnatomyAtlasesCellsConsensusDataData AnalysesData CollectionData SetData Storage and RetrievalEnsureEnvironmentEquipmentFAIR principlesHigh Performance ComputingHumanHuman BioMolecular Atlas ProgramHuman ResourcesImageIngestionLearningLinkMapsMetadataModalityMolecularOntologyOrganOutputPancreasPositioning AttributeProceduresProcessProtocols documentationReproducibilityResolutionResourcesRoleSecureSignal TransductionSystems BiologyTexasTissuesUniversitiesWorkaustinbasecomputerized data processingdata formatdata ingestiondata integrationdata qualitydata sharingexperienceextracellularinteroperabilitymultiple omicsnovelopen source toolspatial relationshiptool
中文摘要
项目摘要
数据分析核心(DAC)负责数据和元数据管理、处理、
该组织地图绘制中心(TMC)及其器官特定项目(OSP)的分析、映射和共享
集中在胰腺上。发改委将通过提供受保护的
用于数据存储和计算的环境,并通过开发健壮的、可重现、可重用和可扩展的
因此,计算工作流可以将数据类型集成到3D地图中以创建
一种交互的、可查询的生物分子人类图谱。DAC是TMC在ITS中的重要组成部分
目的制作并向蜂巢提供广泛的高分辨率分子空间映射
实体,使用开放格式,并在联合国
胰腺。
具体地说,我们将:(1)接收和处理TMC数据集;(2)分析数据集以支持生成
多比例、多参数组织图;(3)构建3D组织图以整合数据集;以及(4)坐标
与HuBMAP联盟一起规划。
英文摘要
PROJECT ABSTRACT
The Data Analysis Core (DAC) is responsible for all aspects of data and metadata management, processing,
analysis, mapping, and sharing for this Tissue Mapping Center (TMC) and its Organ Specific Project (OSP)
focused on the pancreas. The DAC will support the TMC in these activities by providing a protected
environment for data storage and computation, and by developing robust reproducible, reusable, and scalable
computational workflows thus enabling the integration of data types into 3D maps for the purpose of creating
an interactive and queryable biomolecular human atlas. The DAC is an important part of the TMC in its
objectives to produce and deliver to the HIVE extensive sets of high-resolution spatial mappings of molecular
entities, using open formats, and within the context of the cellular and extracellular organization of the
pancreas.
Specifically, we will: (1) ingest and process TMC datasets; (2) analyze datasets in support of generating
multiscale, multiparameter tissue maps; (3) construct 3D tissue maps to integrate datasets; and (4) coordinate
planning with the HuBMAP Consortium.
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专著(0)
科研奖励(0)
会议论文
Data Analysis Core
-
批准号:10685588
-
项目类别:
-
资助金额:$24.74万
-
财政年份:2020
-
负责人:James Paul Carson
-
依托单位:
Multi-omic 3D tissue maps for a Human BioMolecular Atlas
-
批准号:10259781
-
项目类别:
-
资助金额:$98.55万
-
财政年份:2020
-
负责人:James Paul Carson
-
依托单位:
Data Analysis Core
-
批准号:10118876
-
项目类别:
-
资助金额:$11.41万
-
财政年份:2020
-
负责人:James Paul Carson
-
依托单位:
Multi-omic 3D tissue maps for a Human BioMolecular Atlas
-
批准号:10118874
-
项目类别:
-
资助金额:$75.07万
-
财政年份:2020
-
负责人:James Paul Carson
-
依托单位:
An Interactive Volumetric Atlas of the Mouse Brain
-
批准号:7771686
-
项目类别:
-
资助金额:$19.69万
-
财政年份:2009
-
负责人:James Paul Carson
-
依托单位:
海外基金