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中文摘要
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项目摘要 数据分析核心(DAC)负责数据和元数据管理、处理、 该组织地图绘制中心(TMC)及其器官特定项目(OSP)的分析、映射和共享 集中在胰腺上。发改委将通过提供受保护的 用于数据存储和计算的环境,并通过开发健壮的、可重现、可重用和可扩展的 因此,计算工作流可以将数据类型集成到3D地图中以创建 一种交互的、可查询的生物分子人类图谱。DAC是TMC在ITS中的重要组成部分 目的制作并向蜂巢提供广泛的高分辨率分子空间映射 实体,使用开放格式,并在联合国 胰腺。 具体地说,我们将:(1)接收和处理TMC数据集;(2)分析数据集以支持生成 多比例、多参数组织图;(3)构建3D组织图以整合数据集;以及(4)坐标 与HuBMAP联盟一起规划。
英文摘要
PROJECT ABSTRACT The Data Analysis Core (DAC) is responsible for all aspects of data and metadata management, processing, analysis, mapping, and sharing for this Tissue Mapping Center (TMC) and its Organ Specific Project (OSP) focused on the pancreas. The DAC will support the TMC in these activities by providing a protected environment for data storage and computation, and by developing robust reproducible, reusable, and scalable computational workflows thus enabling the integration of data types into 3D maps for the purpose of creating an interactive and queryable biomolecular human atlas. The DAC is an important part of the TMC in its objectives to produce and deliver to the HIVE extensive sets of high-resolution spatial mappings of molecular entities, using open formats, and within the context of the cellular and extracellular organization of the pancreas. Specifically, we will: (1) ingest and process TMC datasets; (2) analyze datasets in support of generating multiscale, multiparameter tissue maps; (3) construct 3D tissue maps to integrate datasets; and (4) coordinate planning with the HuBMAP Consortium.
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Data Analysis Core
Multi-omic 3D tissue maps for a Human BioMolecular Atlas
Data Analysis Core
Multi-omic 3D tissue maps for a Human BioMolecular Atlas
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