Population Science Program

13.0摘要：人口科学(PS)计划 PS计划的总体目标是确定癌症病因、癌症相关行为、 并将基本发现转化为行为干预措施，以预防和控制癌症。至 为了实现这些目标，该方案侧重于三个目标：目标1：感染流行病学--和激素-- 相关癌症，以确定感染和激素相关的分子、遗传和生活方式决定因素 美国和全球癌症；目标2：在癌症预防和早期发现方面的公平，以确定 心理社会对癌症相关健康行为的影响，并开发和评估促进 建议的癌症相关行为，特别是在医疗服务不足的人群中；和目标3：癌症 结果，以确定癌症治疗相关疼痛的机制，并表征个人，治疗， 以及社区层面对癌症预后差异的影响。PS计划有41名成员，包括 24名正式成员和17名准成员，他们进行以癌症为重点的研究，由770万美元资助 年度直接成本资金(总计1010万美元)，包括NCI提供的92万美元(12%)和其他来源的530万美元 同行评议的资料来源。PS计划成员每年从非同行审查的资金中获得140万美元 消息来源。在这一资助期间，PS成员撰写了396份与癌症有关的出版物，其中23% 来自方案内，15%来自方案间，4%来自方案内和方案间 合作。在这些出版物中，85%包括与外部调查人员的合作，反映出 PS计划对全国的影响。在PS出版物中，有10%的出版物具有≥10的影响因子。 广泛使用生物统计学(BSS)和基因组学(GSS)共享服务并提供广泛的培训 机遇。PS计划非常关注癌症差异和为个人提供服务的研究 UMGCCC集水区。这包括与社区外展和参与的密切关系 (COE)优先开展集水区癌症研究，开展社区癌症控制活动，并整合 COE进入PS研究。

13.0 Abstract: Population Science (PS) Program The overall goals of the PS Program are to identify determinants of cancer etiology, cancer-related behavior, and outcomes, and to translate basic discovery into behavioral interventions to prevent and control cancer. To achieve these goals, the program focuses on three aims: Aim 1: Epidemiology of infection- and hormone- related cancers, to identify the molecular, genetic, and lifestyle determinants of infection- and hormone-related cancers in the United States and globally; Aim 2: Equity in cancer prevention and early detection, to identify psychosocial influences on cancer-related health behaviors and to develop and evaluate interventions that foster recommended cancer-related behaviors, particularly in medically underserved populations; and Aim 3: Cancer outcomes, to identify mechanisms of cancer treatment-related pain and to characterize individual-, treatment-, and community-level influences on disparities in cancer outcomes. The PS Program has 41 members, including 24 full members and 17 associate members, who conduct cancer-focused research supported by $7.7 million annual direct cost funding ($10.1 million total), including $0.92 million (12%) from NCI and $5.3 million from other peer-reviewed sources. PS Program members receive $1.4 million annually from non–peer-reviewed funding sources. During this funding period, PS members authored 396 cancer-related publications, of which 23% resulted from intraprogrammatic, 15% from interprogrammatic, and 4% from intra and interprogrammatic collaborations. Of these publications, 85% include collaborations with external investigators, reflecting the high national impact of the PS Program. Of the PS publications, 10% have an impact factor ≥10. PS faculty make extensive use of the Biostatistics (BSS) and Genomics (GSS) shared services and provide extensive training opportunities. The PS Program has a strong focus on cancer disparities and on research serving individuals in the UMGCCC catchment area. This includes a close relationship with Community Outreach and Engagement (COE) to prioritize catchment area cancer research, conduct community cancer control activities, and integrate COE into PS research.