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中文摘要
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摘要 行政核心代表行政、培训、协调和监督部分 布里格姆妇女医院(BWH)临床研究核心中心(CCCR)。BWH CCCR, Verity(使用生物信息学和高级分析在风湿学中的价值和证据),利用 博爱医院和哈佛医学院附属医院的资源,为 由NIAMS任务定义的地方和国家临床研究人员社区。提供的服务 通过方法和生物信息学资源核心响应我们已确定的更好地访问 一系列完整的试验和生物信息学方法,以简化和易于访问的格式组织。 行政核心包含一个创新的充实计划,以培训和指导儿科和成人 风湿病和肌肉骨骼(MSK)临床研究人员,当地和国家。浓缩物 该计划建立在儿科和成人培训计划主任的初步全国调查数据的基础上 描述对临床研究培训和持续研究指导的需求。的总体目的 Verity的行政核心是建立一个由初级和高级调查人员组成的有效社区 朝着改善炎症性风湿病和MSK疾病的治疗和结果的共同目标前进。 此外,行政核心对方法和方法的所有方面进行科学监督 生物信息学资源核心。这些目标是通过以下具体目标实现的:目标 1.促进和监督方法学和生物信息学的科学和行政工作 资源核心,以便以高效和负责任的方式满足研究界的需求 举止。目的2.培养和指导下一代风湿病临床研究人员。 总之,Verity行政核心将为以下方面提供有效的科学和行政监督 确保最佳使用方法学和生物信息学资源核心服务。此外,浓缩铀 该计划将吸引、教育和指导下一代临床研究人员,以增强儿科和 美国成人风湿病和MSK疾病研究。
英文摘要
ABSTRACT The Administrative Core represents the executive, training, coordinating and oversight component of the Brigham and Women’s Hospital (BWH) Core Centers for Clinical Research (CCCR). The BWH CCCR, VERITY (Value and Evidence in Rheumatology using bioInformaTics, and advanced analYtics), taps into the resources of the BWH and Harvard Medical School (HMS) affiliated hospitals to offer services to the community of clinical investigators defined by the NIAMS mission, locally and nationally. The services provided by the Methods and Bioinformatics Resource Cores respond to needs we have identified for better access to a complete array of trial and bioinformatics methods organized in a streamlined and readily accessible format. The Administrative Core contains an innovative Enrichment Program to train and mentor pediatric and adult rheumatic and musculoskeletal (MSK) clinical researchers, both locally and nationally. The Enrichment Program builds on preliminary national survey data of pediatric and adult training program directors characterizing the need for clinical research training and ongoing research mentoring. The overall purpose of the VERITY Administrative Core is to develop an effective community of junior and senior investigators working toward the common goal of improving treatment and outcomes of inflammatory rheumatic and MSK disease. In addition, the Administrative Core provides scientific oversight of all aspects of the Methodology and Bioinformatics Resource Cores. These objectives are accomplished through the following Specific Aims: Aim 1. To facilitate and supervise the scientific and administrative work of the Methodology and Bioinformatics Resource Cores, so that the needs of the Research Community are met in an efficient and responsible manner. Aim 2. To train and mentor the next generation of clinical researchers in rheumatology. In sum, the VERITY Administrative Core will provide effective scientific and administrative oversight to ensure optimal use of the Methodology and Bioinformatics Resource Core services. Moreover, the Enrichment Program will attract, educate, and mentor the next generation of clinical researchers to enhance pediatric and adult rheumatic and MSK disease research in the US.
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Rheumatoid Arthritis and the Risk of Cardiovascular Disease: Biomarkers Risk Prediction and Underlying Mechanisms
  • 批准号:
    10416473
  • 项目类别:
  • 资助金额:
    $68.32万
  • 财政年份:
    2022
  • 负责人:
    Daniel Hal Solomon
  • 依托单位:
Rheumatoid Arthritis and the Risk of Cardiovascular Disease: Biomarkers Risk Prediction and Underlying Mechanisms
  • 批准号:
    10643971
  • 项目类别:
  • 资助金额:
    $74.63万
  • 财政年份:
    2022
  • 负责人:
    Daniel Hal Solomon
  • 依托单位:
VERITY: Value and Evidence in Rheumatology using bioInformaTics, and advanced analYtics
  • 批准号:
    9768189
  • 项目类别:
  • 资助金额:
    $89.49万
  • 财政年份:
    2017
  • 负责人:
    Daniel Hal Solomon
  • 依托单位:
VERITY: Value and Evidence in Rheumatology using bioInformaTics, and advanced analYtics
  • 批准号:
    10017653
  • 项目类别:
  • 资助金额:
    $89.39万
  • 财政年份:
    2017
  • 负责人:
    Daniel Hal Solomon
  • 依托单位:
海外基金