PPE Request

项目总结/摘要 为了应对COVID-19大流行的挑战，波士顿儿童医院（BCH）要求并收到了 NIAID资助U19 AI 118608“人类疫苗反应的个体发生”的行政补充， 2019冠状病毒病队列免疫表型评估（IMPACC）临床和数据协调中心 （CDCC）。IMPACC研究是一项观察性队列研究，收集了详细的临床、实验室和影像学资料。 数据与血液和呼吸道分泌物的生物采样以及鼻腔中的病毒脱落相协调 以确定COVID-19相关易感性的免疫表型和基因组特征 和/或进展，以产生有效的宿主导向治疗干预的假设， 优先考虑此类干预措施的建议，和/或优化宿主反应管理的时机 定向治疗 IMPACC研究中的许多研究中心缺乏足够的PPE来保护与住院患者互动的所有研究中心工作人员。 新冠肺炎患者。因此，IMPAC CDCC寻求额外的资源，以分配给参与 网站. RhoFED通过采购必要的额外PPE来满足这一需求，其中包括口罩， 带眼罩的面罩、长袍、手套和面罩。

PROJECT SUMMARY / ABSTRACT To meet the challenge of the COVID-19 pandemic, Boston Children's Hospital (BCH) requested and received an administrative supplement to NIAID grant U19AI118608 “Ontogeny of Human Vaccine Responses” to fund the Immunophenotyping Assessment in a COVID-19 Cohort (IMPACC) Clinical and Data Coordinating Center (CDCC). The IMPACC study is an observational cohort collecting detailed clinical, laboratory, and radiographic data in coordination with biologic sampling of blood and respiratory secretions and viral shedding in nasal secretions in order to identify immunophenotypic and genomic features of COVID-19–related susceptibility and/or progression in order to generate hypotheses for effective host-directed therapeutic interventions, to help to prioritize proposals for such interventions, and/or optimize timing for administration of host-response directed therapeutics. Many sites in the IMPACC study lacked sufficient PPE to protect all study site staff interacting with hospitalized COVID-19 patients. Therefore, the IMPACC CDCC sought additional resources to distribute to the participating sites. RhoFED responded to this need by procuring the necessary additional PPE, which consisted of masks, masks with eye shields, gowns, gloves, and face shields.