Center for AIDS Prevention Studies (CAPS)

项目总结 艾滋病预防研究中心(CAPS)是一个高效、充满活力、综合的、多学科的 该中心进行尖端、高影响力的艾滋病毒预防研究，并得到来自 全国排名最高的医学院之一。CAPS拥有一支多学科的教职员工，负责 由中心的使命推动的研究。CAPS对艾滋病毒科学的重大贡献在过去几年中是显而易见的 在本授奖期间(2016年9月1日至2020年6月30日)出版了553份手稿。CAPS一直在继续 通过获得NIH研究拨款来催化艾滋病毒科学，成功率接近60%，并已成长为 多样化的组合，解决艾滋病毒预防和治疗的连续性问题。此产品组合涵盖基本功能 社会和行为科学，以干预发展，实施和政策研究。重要的 CAPS正在进行的科学贡献使该中心有必要继续在推动 结束艾滋病毒流行所需的下一代研究。 我们将继续为推动学科建设的一批世界级科学家干部提供关键支持 边界。这将通过一个灵活的研究核心基础设施来实现，该基础设施旨在点燃科学 具有达到全球指标所需的深度和广度的创新和高影响力研究 结束这场流行病。总体而言，CAPS的目标是： 1.催生强大的科学环境：点燃及时、创新、高影响、多学科 研究灵活处理对结束艾滋病毒流行至关重要的当前和新出现的问题，特别是 与中心主题相关的主题； 2.加强科技队伍建设：建设数量、能力、能力、效益和 调查人员的多样性，以及社区和公共卫生合作伙伴，以进行高优先级、高质量的 影响艾滋病毒研究，以应对推动艾滋病毒的共生和多重因素 和与艾滋病毒有关的卫生系统； 3.推进创新方法：推广使用新颖的研究设计、综合方法和 解决复杂、多层次、共生、 促进而不是阻碍获得艾滋病毒预防和治疗的多重因素和战略 艾滋病毒相关卫生系统内的治疗； 4.最大限度地提高公共健康影响：通过支持研究来弥合研究与实践之间的差距 这确保有效的干预和做法以最佳和公平的方式转化为有效的 在不同的社区和卫生系统内和跨不同的社区和卫生系统实施。 综上所述，与NIMH艾滋病研究部的高度优先领域一致，3个上限将推动 通过催化和支持创新的、多学科的艾滋病毒，在结束艾滋病毒流行方面取得进展 整合和维持跨不同卫生系统的艾滋病毒预防和治疗服务的研究 解决推动疫情的共生和倍增因素。

PROJECT SUMMARY The Center for AIDS Prevention Studies (CAPS) is a highly productive, vibrant, integrated, multidisciplinary center that conducts cutting-edge, high-impact HIV prevention research with robust institutional support from one of the highest ranked medical schools in the country. CAPS has a multidisciplinary faculty who conduct research driven by the center's mission. CAPS's significant contributions to HIV science are evident in the over 553 manuscripts published during the current award period (9/01/2016-6/30/2020). CAPS has continued to catalyze HIV science by obtaining NIH research grants at an almost 60% success rate and has grown a diverse portfolio that addresses the continuum of HIV prevention and treatment. This portfolio spans basic social and behavioral science to intervention development, implementation and policy research. The significant and ongoing scientific contributions of CAPS necessitate the center continue its leadership in advancing the next generation of research required to end the HIV epidemic. We will continue to provide critical support to a cadre of world-class scientists who push disciplinary boundaries. This will be accomplished via an agile infrastructure of research cores designed to ignite scientific innovation and high-impact research with the depth and breadth necessary to reach global indicators for ending the epidemic. Overall, CAPS aims to: 1. Catalyze a strong scientific environment: Ignite timely, innovative, high-impact, multidisciplinary research to nimbly address current and emerging issues critical for ending the HIV epidemic, particularly those related to the center themes; 2. Strengthen the scientific workforce: Build the number, competence, capacity, effectiveness, and diversity of investigators, as well as community and public health partners to conduct high-priority, high- impact HIV research that is responsive to addressing co-occurring and multiplicative factors driving HIV and HIV-related health systems; 3. Advance innovative methods: Promote the use of novel research designs, integrative methods, and cutting-edge technologies that are necessary for addressing the complex, multilayered, co-occurring, multiplicative factors and strategies that facilitate rather than hinder access to HIV prevention and treatment within HIV-related health systems; 4. Maximize public health impact: Bridge the gap between research and practice by supporting research that ensures that efficacious interventions and practices translate optimally and equitably into effective implementation within and across diverse community and health systems. In summary, consistent with NIMH Division of AIDS Research's areas of high priority,3 CAPS will drive progress towards an end to the HIV epidemic by catalyzing and supporting innovative, multidisciplinary HIV research that integrates and sustains HIV prevention and treatment delivery across diverse health systems to address the co-occurring and multiplicative factors that drive the epidemic.