Technologies for Solid-State NMR Data Collection

TR & D 2摘要 NMR光谱仪的整体性能会影响每个研究样本和结果。经常为 复杂的多维魔角旋转固态核磁共振实验，几十个实验 参数需要仔细调整，并且在环境条件漂移的任何时候都必须重新调整。这里 提出了加速这种实验的设置和配置的方法，以最大限度地利用 可用的仪器时间，以及在长时间的信号平均中保持性能， 对于数量有限的珍贵研究样本，可能需要使用。的所有方面 实验性能还严重依赖于NMR探针设计，包括射频 电子电路和相关的接口，以旋转样品，控制温度，并提供均匀的 脉冲磁场作为现代多维NMR实验的一部分。

TR&D 2 SUMMARY The overall performance of the NMR spectrometer impacts every research sample and outcome. Often for complex multidimensional magic-angle spinning solid-state NMR experiments, dozens of experimental parameters require careful adjustment and must be readjusted anytime the environmental conditions drift. Here proposed are approaches to accelerate the setup and configuration of such experiments to maximally leverage the available instrument time, as well as to maintain performance over long periods of signal averaging that can be required for precious research samples that are available only in limited quantity. All aspects of the experimental performance also rely critically on the NMR probe designs, including the radiofrequency electronic circuits and related interfaces to spin the sample, control the temperature and deliver homogeneous pulsed magnetic fields as part of modern multidimensional NMR experiments.