Novel antibiotics that harness innate immunity to overcome multi-drug resistant S. aureus
Novel antibiotics that harness innate immunity to overcome multi-drug resistant S. aureus
批准号:
nhmrc : 2003325
负责人:
金额:
$87.24万
依托单位国家:
澳大利亚
项目类别:
Ideas Grants
财政年份:
2021
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2021-01-01 至 2023-12-31
中文摘要
用抗生素控制感染在医学上是必不可少的。然而,细菌对抗生素的耐药性正在迅速增长。在这里,我们提出了治疗多重耐药金黄色葡萄球菌的新策略,将现有的临床抗生素与靶向免疫反应相结合,或者通过消除细菌隐藏在我们免疫系统中的能力。这些新方法将使我们能够克服由耐药细菌引起的感染,这是一个严重且日益严重的问题。
英文摘要
Controlling infection with antibiotics is essential in medicine. However, bacterial resistance to antibiotics is growing rapidly. Here, we propose new strategies to treat multi-drug resistant Staphylococcus aureus by combining existing clinical antibiotics with either a targetted immune response or by removing the ability of bacteria to hide from our immune system. These novel approaches will allow us to overcome infections caused by resistant bacteria, which are a serious and growing problem.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
海外基金