Momentary Bio-Behavioral Predictors of Loss of Control Eating and Weight Outcomes

失控饮食和体重结果的瞬间生物行为预测指标 项目摘要/摘要 失控饮食(LOC)对肥胖者来说是个问题，因为它对体重有负面影响 亏损的努力。尽管减肥手术是其中最有效的减肥干预措施 在人群中，手术后进食LOC一再与不良的体重结果有关。这突出了 阐明进食低脂食物的生物行为机制是改善饮食习惯的重要步骤 减肥手术后的体重结果。理论和经验证据支持自我控制(即， 抑制控制)，作为负面影响(NA)促使摄入低碳水化合物的机制。而当 在饮食失调和肥胖人群中使用回溯性自我报告进行传统测量 问卷，这一机械过程尚未在自然环境中进行实时检查 减肥手术的病人。此外，有越来越多的证据表明，低血糖(即， 低血糖)可能影响这一人群中抑制性控制和低脂饮食之间的关系。 因此，拟议的项目试图测试NA、抑制性控制、 低血糖，实时进食LOC，并检查它们对纵向体重的集体贡献 减肥手术后的结果。具体地说，这个项目将测试一个协调的调解模型假设 抑制控制的短暂缺陷将在NA和LOC摄入之间的关系中起中介作用。此外， 这是假设，低血糖将缓和抑制控制和低脂饮食之间的效果。 总体而言，我们预计更频繁和更严重的LOC进食是由于 消极情绪、抑制性控制和低血糖将预测较差的体重结果。 在接下来的一年。通过确定进食低碳水化合物的瞬间机制，这项研究有可能 告知旨在减少术后进食LOC的治疗干预努力，并促进更优化的 体重结果。

Momentary bio-behavioral predictors of loss of control eating and weight outcomes PROJECT SUMMARY/ABSTRACT Loss of control (LOC) eating is problematic for individuals with obesity due to its’ negative impact on weight loss efforts. Despite bariatric surgery being the most effective intervention for weight loss among this population, LOC eating following surgery has been repeatedly linked to poor weight outcomes. This highlights the importance of elucidating bio-behavioral mechanisms of LOC eating as an important step in improving weight outcomes following bariatric surgery. Theoretical and empirical evidence supports self-control (i.e., inhibitory control) as the mechanism through which negative affect (NA) prompts LOC eating. While traditionally measured among populations with eating disorders and obesity using retrospective self-report questionnaires, this mechanistic process has yet to be examined in real-time in the natural environment of bariatric surgery patients. Additionally, there is accumulating evidence that low blood glucose (i.e., hypoglycemia) may impact the relationship between inhibitory control and LOC eating among this population. Therefore, the proposed project seeks to test the prospective relationships between NA, inhibitory control, hypoglycemia, and LOC eating in real-time and examine their collective contribution on longitudinal weight outcomes post-bariatric surgery. Specifically, this project will test a moderated mediation model hypothesizing that momentary deficits in inhibitory control will mediate the relationship between NA and LOC eating. Further, it is hypothesized that hypoglycemia will moderate the effect between inhibitory control and LOC eating. Collectively, we anticipate that the more frequent and severe LOC eating resulting from the interplay between negative affect, inhibitory control, and hypoglycemia will then prospectively predict a poorer weight outcome over the following year. By identifying momentary mechanisms of LOC eating, this research has the potential to inform treatment intervention efforts aimed at reducing LOC eating post-surgery and promote more optimal weight outcomes.