Biomedical Statistics Core

生物医学统计核心 饮食行为生物行为机制中心 总结/摘要 我们建议在桑福德生物中心建立一个生物医学研究卓越中心（COBRE）， 行为研究（SCBR;法戈，ND）与北达科他州州立大学（NDSU）合作 心理学系和药学系以及北达科他州大学 医学（联索援助团）。该中心将专注于进行尖端的创新研究， 与饮食失调和饮食行为的发生和维持有关的机制。的目的 生物医学统计核心（BSC）是建立一个方法和统计基础设施， 临床和转化研究和教育的重点是发病机制， 饮食失调和饮食行为的维持。这一核心将使人们能够有效地利用 通过提供咨询、方法和统计支持服务， 教育活动以及方法和统计方面的指导和培训机会。 目标 1.在桑福德生物行为研究中心制定和实施平衡计分卡， 保持高质量的方法和统计咨询和支持服务的临床和 与进食障碍的发生和维持有关的机制的转化研究， 饮食行为。 2.为COBRE项目主任提供方法和统计教育机会， 教师以研讨会，座谈会和讲习班的形式。这些教育机会将侧重于 识别和评估机械过程的方法。 3.为COBRE项目主管和教员提供指导和实践培训机会 有兴趣获得分析经验，进一步发展他们的统计和方法技能。 方法 BSC将与COBRE项目总监在授予前、授予后和授予后期间合作， 协助研究设计、样本量计算、功效分析、数据收集方法、数据存储和 管理、正在进行的研究监查、统计分析、结果解释和协助 准备演讲和出版物。平衡计分卡将与行政核心和人力资源部合作， 提供研究伦理行为领域的相关培训机会， 研究设计（例如，样本量计算和功效分析），机械数据分析方法， 资助写作和专业发展。除了这些培训机会，BSC还将 以持续指导或定期实践培训的形式为项目提供更密集的培训 有兴趣扩展其分析能力的董事。

Biomedical Statistics Core Center for Bio-behavioral Mechanisms of Eating Behavior SUMMARY/ABSTRACT We propose to establish a Center of Biomedical Research Excellence (COBRE) at the Sanford Center for Bio- behavioral Research (SCBR; Fargo, ND) in collaboration with the North Dakota State University (NDSU) Departments of Psychology and Pharmaceutical Sciences and the University of North Dakota School of Medicine (UNDSOM). This center will focus on conducting cutting-edge, innovative research on the mechanisms related to the onset and maintenance of eating disorders and eating behaviors. The purpose of the Biomedical Statistics Core (BSC) is to create a methodological and statistical infrastructure supporting clinical and translational research and education focused on the mechanisms related to the onset and maintenance of eating disorders and eating behaviors. This core will allow efficient access to methodological and biostatistical support by providing consultation, methodological and statistical support services, educational activities, and methodological and statistical mentoring and training opportunities. Objectives 1. To develop and implement a BSC at Sanford Center for Bio-behavioral Research that will provide and maintain high quality methodological and statistical consultation and support services for clinical and translational research on the mechanisms related to the onset and maintenance of eating disorders and eating behaviors. 2. To provide methodological and statistical educational opportunities for COBRE Project Directors and faculty in the form of seminars, colloquia, and workshops. These educational opportunities will focus on methods for identifying and evaluating mechanistic processes. 3. To provide mentoring and hands-on training opportunities for COBRE Project Directors and faculty interested in gaining analytic experience and further developing their statistical and methodological skills. Methods The BSC will work with the COBRE Project Directors during the pre-grant, grant, and post-grant periods, assisting in study design, sample size calculation, power analysis, data collection methods, data storage and management, ongoing study monitoring, statistical analysis, interpretations of results, and assistance in preparation of presentations and publications. The BSC will work with the Administrative Core and Human Subjects Core to provide relevant training opportunities in the areas of the ethical conduct of research, research design (e.g., sample size calculation and power analysis), mechanistic data analytic approaches, grant writing, and professional development. In addition to these training opportunities, the BSC will also provide more intensive training in the form of ongoing mentoring or regular hands-on training for Project Directors who are interested in expanding their analytic capabilities.