Basic Science Core - Biosafety & Biocontainment Core (BBC)

德克萨斯州Bimed In-TRAC生物安全和生物遏制核心(BBC)-摘要 这个核心的目标是为下一步建立个性化的生物安全和生物遏制培训课程 一代结核病(TB)研究人员，为他们在生物遏制下工作和出类拔萃做好准备 环境进行研究，以推动该领域的发展。对于从事结核病研究的新调查员以及 想要进入结核病研究领域的资深研究人员，对他们来说了解 生物安全和生物遏制环境，包括工作的优势和局限性的知识 在生物遏制方面，为了让他们实现他们的职业目标。正确进行风险评估的能力 包括对生物遏制中的设备和程序的透彻了解，将进一步确保 结核病研究方面的创新，特别是在资源有限的领域。我们的目标是：目标1.建立和管理 个性化的生物安全与生物遏制课程。为实现这一目标，采取分阶段的方法(评估和 教学阶段)将实施，以提供全面和定制的培训。目标2.执行一项 生物安全和生物遏制培训计划--《TRAC》参与者。在这个目标中，一个个性化的 将执行为每一名IN-TRAC参与者建立的生物遏制培训计划。参与者将 了解如何在高密封性的BSL3设施中安全有效地运行。我们将把它分成三部分 分部：生物遏制设施操作、一般程序和应急演习。目标3. 将风险评估和缓解策略应用于新兴技术和多种危险情景。 新技术往往会带来不可预见的生物安全风险。配备普通生物遏制装置和结核分枝杆菌 特定于程序的知识，参与者将能够在以下情况下正确评估和实施程序 遇到新兴技术并开发安全程序以实现他们的研究目标。 完成这一核心课程后，新的结核病研究人员将准备/熟练地在 生物遏制环境，包括在结核病领域取得成功所需的一般和专门技术。 重要的是，IN-TRAC参与者将准备一份关于优势和劣势的书面和口头总结 关于In-TRAC计划的经验。

Texas Biomed IN-TRAC Biosafety & Biocontainment Core (BBC) – ABSTRACT The goal of this core is to establish a personalized Biosafety & Biocontainment training curriculum for the next generation of tuberculosis (TB) researchers in order to prepare them to work and excel within the biocontainment environment performing studies to advance the field. For a new investigator pursuing TB research as well as for well-established investigators who want to enter the TB research field, it is critical for them to understand biosafety and the biocontainment environment, including knowledge of the strengths and limitations of working in biocontainment, in order for them to achieve their career goals. The ability to properly conduct risk assessment including a thorough understanding of equipment and procedures in biocontainment, will further ensure innovations in TB research, especially in resource limited areas. Our Aims are to: Aim 1. Establish and manage a personalized Biosafety & Biocontainment curriculum. In this Aim a phased approach (assessment and didactic phases) will be implemented to provide comprehensive and customized training. Aim 2. Execute a Biosafety & Biocontainment training program for IN-TRAC participants. In this aim, a personalized Biocontainment training program established for each IN-TRAC participant will be executed. Participants will learn how to function safely and effectively in a high-containment BSL3 facility. We will divide this into three segments: Biocontainment facility operations, General Procedures and Emergency Response Drills. Aim 3. Apply risk assessment and mitigation strategies to emerging technology and multi-hazard scenarios. New technology often introduces unforeseeable biosafety risks. Equipped with general biocontainment and M.tb procedure-specific knowledge, participants will be able to properly evaluate and implement procedures when encountering emerging technology and develop procedures to safety achieve their research goals. Upon completion of this core curriculum, new TB researchers will be prepared/proficient in working in a biocontainment environment, including general and specialized techniques required for success in the TB field. Importantly, IN-TRAC participants will prepare a written and oral summary about the strengths and weaknesses of experience for the IN-TRAC program.