Human Physiology Core

人体生理学核心提供最先进的，具有成本效益的，集中的服务， 生化分析物、人体成分和能量代谢、胰岛素敏感性和β细胞功能 用于糖尿病相关的研究。为此目的，核心保持文书，收集和提供 质量控制数据，维护和提供基于网络的调度系统，并提供训练有素的人员配置 技术人员提供广泛的措施和服务，以满足小型试点的需要 研究和学生项目到大型R01级协议。此外，核心促进多学科 在整个UAB校园的糖尿病研究，并提供培训，建议，并指导学生，研究员， 教师。最后，核心有助于发展，演变，并扩大在该领域的方法 通过实施和验证新的技术和方法，在UAB糖尿病。新技术在此 项目期间包括通过磁共振成像分析肾窦脂肪。开发工作包括 使用干血斑分析来自提供远程样本的研究参与者的激素。人类 生理学核心在DRC中发挥着核心作用，将基础研究成果转化为理解 人类生理和病理生理机制导致糖尿病和心脏代谢疾病。

The Human Physiology Core provides state-of-the-art, cost-effective, centralized services for assessment of biochemical analytes, human body composition and energy metabolism, insulin sensitivity, and beta-cell function for diabetes-related research studies. Toward this end, the Core maintains instruments, collects and provides quality control data, maintains and offers a web-based scheduling system, and provides staffing by trained technical personnel for a broad suite of measures and services that can accommodate the needs of small pilot studies and student projects up to large R01-level protocols. In addition, the Core promotes multi-disciplinary research in diabetes across the UAB campus, and offers training, advice, and instruction to students, fellows, and faculty. Lastly, the Core contributes to the development, evolution, and expansion of methodology in field of diabetes at UAB by implementing and validating new technology and methodology. New technology offered in this project period includes analysis of renal sinus fat from magnetic resonance imaging. Developmental work includes use of dried blood spots for analysis of hormones from study participants providing remote samples. The Human Physiology Core plays a central role in the DRC in the translation of basic research findings into an understanding of human physiology and pathophysiological mechanisms causing diabetes and cardiometabolic disease.