Summer Program for Undergraduate Rising Stars (SPURS), a Columbia University biomedical sciences pipeline program

项目摘要 此申请是R25 NS 076445的竞争性更新，以资助“夏季计划下， 代表学生（SPURS）”，将更名为“本科新星暑期项目 （SPURS）"，通过RFA-HL-21-168机制。100%的资金将用于支持 SPURS的学生从事神经科学项目的核心NINDS的使命。SPURS将提供 密集的本科生生物医学研究经验，为有才华的非洲裔美国人/黑人，西班牙裔 拉丁美洲人（a），美洲原住民/阿拉斯加原住民，太平洋岛民，第一代，经济上处于不利地位 哥伦比亚大学神经科学系的学生。SPURS每年将培养14名优秀学生 他们是主修神经科学和生物医学研究相关领域的本科生。哥伦比亚 大学的SPURS计划提供了一个激烈的本科生在校园里的研究经验， 哥伦比亚的内科医生和外科医生学院（P&S）为来自以下背景的有才华的学生提供 在生物医学研究中的代表性不足。SPURS的参与者是从纽约城市大学接受的 约克（纽约市立大学）高级学院，包括亨特学院、布鲁克林学院、皇后学院和城市学院，以及大学 全国的大学。SPURS提供基础和转化神经科学的广泛培训 研究，并提高了学生将通过追求科学事业的可能性， 高级学位（医学博士）和/或博士）。扩大代表性不足的少数民族本科生的机会 学生参与高质量，集中和持续的研究经验，在神经科学， SPURS计划利用神经科学领域的优秀资源和教师导师。在过去 在资助期间，申请人数激增，在即将到来的时期，我们建议继续高度培训 合格的少数民族学生参加。学生们在夏季的九个星期里进行实践研究， NINDS支持的哥伦比亚大学神经科学家的导师（目前哥伦比亚大学89名 研究人员得到NINDS的支持）。除了神经科学的具体培训外，学生们还 接受了深入的研究方法培训，包括：（a）实验设计和分析;（B） 通过期刊俱乐部和科学伦理讨论批判性地阅读科学文献;（c） 在实验室会议上介绍科学成果;（d）在海报展示会上介绍其研究成果; (e)向科学家听众口头介绍他们的研究;（f）职业咨询。最后 研究培训将在一个独特的丰富的设置，包括每周会议， 在生物医学研究中代表了少数群体的榜样。SPURS计划解决了以下关键需求： 增加高素质少数民族受训人员进入神经科学的渠道。

PROJECT SUMMARY This application is for a competitive renewal of R25 NS076445 to fund “Summer Program for Under- represented Students (SPURS)”, to be renamed “Summer Program for Undergraduate Rising Stars (SPURS)”, through the RFA-HL-21-168 mechanism. 100% of the proposed funding will be used to support SPURS students working on neuroscience projects central to the mission of NINDS. SPURS will provide an intensive, undergraduate biomedical research experience for talented African-American/Black, Hispanic Latino(a), Native American/Alaska Native, Pacific Islander, first-generation, and economically disadvantaged students in the neurosciences at Columbia University. SPURS will train 14 outstanding students each year who are undergraduates majoring in areas relevant to neuroscience and biomedical research.Columbia University's SPURS Program provides an intense undergraduate research experience on the campus of Columbia's College of Physicians & Surgeons (P&S) for talented students from backgrounds that are under-represented in biomedical research. SPURS participants are accepted from the City University of New York (CUNY) senior colleges, including Hunter, Brooklyn, Queens, and City Colleges, as well as universities and colleges nationwide. SPURS provides extensive training in basic and translational neuroscience research, and enhances the likelihood that the students will achieve a career in science by pursuing an advanced degree (M.D. and/or Ph.D.). To expand opportunities for under-represented minority undergraduate students to participate in high quality, focused and sustained research experiences in the neurosciences, the SPURS program leverages outstanding resources and faculty mentors in the neurosciences. Over the last funding period, applications have soared and in the upcoming period, we propose to continue training highly qualified minority student participants. Students perform hands-on research for nine summer weeks under the mentorship of NINDS-supported Columbia University neuroscientists (currently 89 Columbia University researchers receive NINDS support). In addition to specific training in neuroscience, the students have received in-depth training in research methodology including: (a) the design and analysis of experiments; (b) critical reading of scientific literature through journal clubs and discussions of ethics in science; (c) the presentation of scientific results at laboratory meetings; (d) presentation of their research at poster sessions; (e) an oral presentation of their research to an audience of scientists; and (f) career counseling. Finally, the research training will be provided in a uniquely enriching setting that includes weekly meetings with under- represented minority role models in biomedical research. The SPURS program addresses the critical need to increase the pipeline of highly qualified minority trainees into neuroscience.