A New Biomedical Research Vivarium at a Hispanic-Serving Institution on the US-Mexico Border

项目摘要 基于动物的生物医学研究是人类健康和经济福祉的重要贡献者， 美国的以动物为基础的生物医学研究的重要性从未像现在这样明显。 在当前的COVID 19大流行期间。动物模型的研究对于理解 疾病进展，改善患者护理，设计和测试疫苗， 这种致命的疾病。目前的大流行病还暴露了我国人口中存在的严重健康差距， 民族COVID 19对非洲裔美国人，西班牙裔和美洲原住民的不成比例的影响 人口问题凸显了我们对少数民族与其他民族如何不同的认识存在根本性差距。 大多数人群的易感性，病理学和对疾病治疗的反应。这 知识差距超越了COVID 19，几乎涵盖了所有健康和行为问题。一 解决这一差距的一个重要办法是扩大研究和研究培训的范围， 少数民族人口较多的社区。新墨西哥州州立大学（NMSU）是一个西班牙裔服务 新兴卓越机构位于美国南部边境，一个高种族， 文化和经济多样性。该项目将资助建设新的野生动物饲养场，鸟舍， NMSU的昆虫饲养所将加强这些不同人群的生物医学研究和培训。这 新建筑将容纳啮齿动物、蝙蝠和鸟类等野生动物疾病模型， 病媒，如蚊子、蜱和臭虫。该建筑还将包括行为观察 和手术室，分析和生理测试实验室，显微镜室和支持空间。这 新的建筑将毗邻和补充一个新的实验动物饲养场已经在建设中的国家 债券融资，包括实验室动物模型，行为和程序室，诊断和 分析实验室、大型手术室和支持空间。这个综合体被称为生物医学 研究设施，将取代和大大扩大后，现有的老化校园动物园，并将带来 一起在一个设施工作的无脊椎动物模型，目前遍布校园。生物医学 研究设施将支持NMSU在新兴传染病，老龄化， 癌症和健康的差距在服务不足的人口，加强培训的学生从代表不足 人口，并促进解决边境社区和少数民族人口健康问题的研究， 新墨西哥州和该地区。

PROJECT SUMMARY Animal-based biomedical research is a critical contributor to human health and economic well-being in the United States. The importance of animal-based biomedical research has never been more apparent than during the current COVID19 pandemic. Work with animal models has been essential for understanding disease progression, improving patient care, designing and testing vaccines and uncovering the origins of this deadly disease. The current pandemic has also unmasked the grave health disparities that exist in our nation. The disproportionate impact of COVID19 on African-American, Hispanic and Native American populations has highlighted a fundamental gap in our knowledge of how minority populations differ from majority populations in susceptibility, symptomology, and response to treatments for diseases. This knowledge gap extends beyond COVID 19 to encompass virtually all health and behavioral issues. One important solution for addressing this gap is to increase the scope of research, and research training, in communities with larger minority populations. New Mexico State University (NMSU) is a Hispanic-serving Institution of Emerging Excellence located on the southern border of the United States, an area of high racial, cultural and economic diversity. This project would fund construction of new wild animal vivarium, aviary and insectary at NMSU that would enhance biomedical research and training for these diverse populations. This new building would house both wild animal disease models such as rodents, bats and birds and invertebrate disease vectors such as mosquitoes, ticks, and bedbugs. The building will also include behavioral observation and procedural rooms, analytical and physiology testing labs, a microscopy room and support space. This new building will adjoin and complement a new lab animal vivarium already under construction with state bond funding that includes housing for lab animal models, behavioral and procedure rooms, diagnostic and analytical labs, a large surgery suite and support space. The combined complex, called the Biomedical Research Facility, will replace and greatly expand upon the existing aging campus vivarium, and will bring together in one facility work on invertebrate models that is currently spread across campus. The Biomedical Research Facility will support NMSU’s biomedical research strengths in emerging infectious diseases, aging, cancer and health disparities in underserved populations, enhance training of students from underrepresented populations, and promote research addressing the health of border communities and minority populations in New Mexico and the region.