Psychosocial Stress Due to COVID-19 and Vascular Aging in African-American Women

COVID-19 造成的心理社会压力和非裔美国女性的血管老化

基本信息

  • 批准号:
    10792341
  • 负责人:
  • 金额:
    $ 37.56万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-05-01 至 2025-03-31
  • 项目状态:
    未结题

项目摘要

PROJECT SUMMARY The novel coronavirus disease 2019 (COVID-19) global pandemic was arguably one of the most devastating Public Health crises of the last century. In the US, African-Americans have been disproportionately impacted, with overall rates of infection and mortality 2 to 4 times higher than those observed in Whites. Additionally, as a direct result of closings of non-essential businesses and other entities, rates of unemployment and underemployment also surged, and African-Americans have been significantly more likely than Whites to report being underemployed or furloughed due to the pandemic. Unsurprisingly, given racial disparities in COVID-19 mortality, national polls also find racial differences in reports of COVID-related loss, with African- Americans more frequently reporting personally knowing someone who died from COVID-19 than Whites. Because of this, it has been argued that, as a result of COVID-19, African-Americans have been experiencing a “pandemic of stress” that will have a “dangerous impact” on their health and well-being long after the virus itself is contained. Leveraging our previously funded cohort that assessed psychosocial stress and vascular aging in early middle-aged African-American women, we will examine the degree to which stressors resulting from, and related to, the COVID-19 pandemic might impact vascular disease—the number 1 killer in the US-in this group. Middle-aged African-American women may be a uniquely important group on which to focus, because: 1) they have increasingly high, but poorly understood, rates of vascular disease relative to other race-gender groups; and 2) the long-term impact of the widespread financial, employment and social stressors resulting from COVID-19 might be particularly deleterious for this group, largely due to structural and contextual inequalities that pre-dated the pandemic itself. The proposed project will examine linkages between overall psychosocial stressors (debt, financial stress, job stress, interpersonal incivilities and mistreatment, loneliness), COVID-specific stressors (COVID-related financial difficulties, COVID-specific parenting stressors, COVID-related loss) and prospective changes in vascular aging (ambulatory blood pressure, arterial stiffness, inflammation) over 24 months in a cohort of 350 middle- aged African-American women. Because we have pre-COVID assessments of a range of psychosocial stressors, a major innovation of the proposed work is our ability to examine how pre- versus post- COVID changes in exposure to overall psychosocial stress might prospectively impact vascular aging. Importantly, we will capitalize on the considerable within-group heterogeneity in our cohort, to examine whether our hypothesized associations are moderated by sociodemographic factors that might increase vulnerability (socioeconomic status, single parenthood, marital status) or resilience (e.g., purpose in life, optimism, mastery, social support) to psychosocial stress, in order to inform short- and long-term prevention efforts.
项目总结 新型冠状病毒病2019(新冠肺炎)的全球大流行可以说是最具破坏性的之一 上个世纪的公共卫生危机。在美国,非裔美国人受到了不成比例的影响, 总体感染率和死亡率是白人的2到4倍。此外,作为一项 关闭非必要企业和其他实体的直接结果、失业率和 就业不足率也大幅上升,非洲裔美国人比白人更有可能 报告由于大流行而未充分就业或暂时休假。不出所料,考虑到 新冠肺炎死亡率,全国民意调查也发现种族差异的报告与新冠病毒相关的损失,与非洲- 与白人相比,美国人更频繁地报告自己认识死于新冠肺炎的人。 正因为如此,有人认为,由于新冠肺炎,非洲裔美国人 经历“压力大流行”,这将对他们的健康和福祉产生“危险的影响” 在病毒本身被控制很久之后。利用我们之前资助的评估心理社会的队列 在早期中年非裔美国女性中,我们将检查压力和血管老化的程度 新冠肺炎大流行导致的以及与之相关的哪些应激源可能会影响血管 疾病--美国的头号杀手--在这个群体中。非洲裔美国中年女性可能是 要重点关注的唯一重要的群体,因为:1)他们越来越高,但了解得很少, 血管疾病相对于其他种族-性别群体的比率;以及2)普遍存在的 新冠肺炎引发的金融、就业和社会压力可能对此尤其有害 这在很大程度上是由于在大流行本身之前的结构性和背景不平等。建议数 该项目将检查总体心理社会压力因素(债务、经济压力、工作压力、 人与人之间的不礼貌和虐待、孤独)、COVID特有的压力源(COVID相关财务 困难、COVID特有的育儿压力源、COVID相关的损失)和血管的预期变化 年龄(动态血压、动脉僵硬、炎症)超过24个月的350名中老年人队列中 上了年纪的非裔美国妇女。因为我们有一系列新冠肺炎前的心理社会评估 压力源,拟议工作的一个主要创新是我们能够检查前后 暴露于整体心理社会应激的COVID变化可能会对血管老化产生预期影响。 重要的是,我们将利用我们队列中相当大的组内异质性,来检查 我们假设的关联受到社会人口统计因素的影响,这些因素可能会增加脆弱性 (社会经济地位,单亲父母,婚姻状况)或韧性(例如,生活目标,乐观,掌握, 社会支持)对心理社会压力的影响,以便为短期和长期预防工作提供信息。

项目成果

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Tené T Lewis其他文献

Tené T Lewis的其他文献

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{{ truncateString('Tené T Lewis', 18)}}的其他基金

Sociocultural Shifting, Sleep and Cardiometabolic Risk in African-American Women
非裔美国女性的社会文化转变、睡眠和心脏代谢风险
  • 批准号:
    10718447
  • 财政年份:
    2023
  • 资助金额:
    $ 37.56万
  • 项目类别:
Mentoring and Patient-Oriented Research on Social Exposures and CVD Risk in Underrepresented Women
针对代表性不足的女性的社会暴露和心血管疾病风险的指导和以患者为导向的研究
  • 批准号:
    10440016
  • 财政年份:
    2022
  • 资助金额:
    $ 37.56万
  • 项目类别:
Mentoring and Patient-Oriented Research on Social Exposures and CVD Risk in Underrepresented Women
针对代表性不足的女性的社会暴露和心血管疾病风险的指导和以患者为导向的研究
  • 批准号:
    10616599
  • 财政年份:
    2022
  • 资助金额:
    $ 37.56万
  • 项目类别:
Diversity Supplement to Psychosocial Stress due to COVID-19 and Vascular Aging in African-American Women
对非裔美国女性因 COVID-19 和血管老化造成的心理社会压力进行多样性补充
  • 批准号:
    10709289
  • 财政年份:
    2021
  • 资助金额:
    $ 37.56万
  • 项目类别:
Psychosocial Stress due to COVID-19 and Vascular Aging in African-American Women
COVID-19 造成的心理社会压力和非裔美国女性的血管老化
  • 批准号:
    10604282
  • 财政年份:
    2021
  • 资助金额:
    $ 37.56万
  • 项目类别:
Diversity Supplement to Psychosocial Stress due to COVID-19 and Vascular Aging in African-American Women
对非裔美国女性因 COVID-19 和血管老化造成的心理社会压力进行多样性补充
  • 批准号:
    10833229
  • 财政年份:
    2021
  • 资助金额:
    $ 37.56万
  • 项目类别:
Psychosocial Stress due to COVID-19 and Vascular Aging in African-American Women
COVID-19 造成的心理社会压力和非裔美国女性的血管老化
  • 批准号:
    10396097
  • 财政年份:
    2021
  • 资助金额:
    $ 37.56万
  • 项目类别:
Chronic Stressors, Brain Vasculature, and Cognitive Function in African-American Women
非裔美国女性的慢性压力源、脑血管系统和认知功能
  • 批准号:
    9308575
  • 财政年份:
    2017
  • 资助金额:
    $ 37.56万
  • 项目类别:
Social Stressors and Atherosclerosis in African-American Women with Lupus
患有狼疮的非洲裔美国女性的社会压力和动脉粥样硬化
  • 批准号:
    9767661
  • 财政年份:
    2016
  • 资助金额:
    $ 37.56万
  • 项目类别:
Expectations of Discrimination and CVD Risk in Africian-American Women
对非裔美国女性的歧视和心血管疾病风险的预期
  • 批准号:
    9206177
  • 财政年份:
    2016
  • 资助金额:
    $ 37.56万
  • 项目类别:

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