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中文摘要
翻译
项目摘要/摘要 本行政副刊旨在表彰多样性、公平性、包容性和可获得性方面的卓越表现 (Deia)Mentorship建议增加一批实习生(三名本科毕业生和三名本科生 学生)申请为期一年的培训岗位,以促进其职业发展。家长资助的目标(R01 AR074417)是为了了解骨质疏松症的遗传风险因素,以确定减少这种影响的新药靶点 巨大的健康负担。父母拨款的SA1是为了识别调节骨量和矿物质的新基因 在反向遗传筛查中,骨密度(BMD)相关基因座的增加。拟议的工作将 通过扩大在SubAim1A的反向遗传筛查中检查的基因数量来补充SA1。就像它 与父母拨款有关,该项目在没有其他变化的情况下向SubAim1A增加了30个额外的体细胞突变体。 该项目包括职业发展计划,为每个人提供量身定做的导师支持,并 帮助抵消成功的社会和人际障碍。PI有成功指导的记录 与此项目的实习生具有相似职业阶段和目标的个人,并展示了他的 通过外展、培训、大学领导和国家服务致力于DeIA。预期的影响 这个项目的好处是学员将获得研究经验、导师支持和职业技能,这些将会增加 提高研究生培养计划的竞争力,推进他们的科学和临床职业道路。 通过这样做,这个项目将扩大参与并促进一批未来生物医学的发展 致力于Deia导师制的研究学者,并成为引领未来的典范 发展适应文化的培训环境。
英文摘要
PROJECT SUMMARY/ABSTRACT This Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility (DEIA) Mentorship proposes to add a cohort of trainees (three postbaccalaureate and three undergraduate students) for one-year training positions to foster their career development. The goal of the parent grant (R01 AR074417) is to understand genetic risk factors for osteoporosis to identify new drug targets to reduce this massive health burden. SA1 of the parent grant is to identify novel genes regulating bone mass and mineral accrual at bone mineral density (BMD)-associated loci in a reverse genetic screen. The proposed work will supplement SA1 by expanding the number of genes examined in the reverse genetic screen in SubAim1A. As it relates to the parent grant, this project adds 30 additional somatic mutants to SubAim1A with no other changes. This project includes a career development plan that provides tailored mentor support to each individual and helps counteract social and interpersonal barriers to success. The PI has a track record of successfully mentoring individuals with similar career stages and goals as the trainees on this project, and has demonstrated his commitment to DEIA through outreach, training, university leadership, and national service. The expected impact of this project is that the trainees will gain research experience, mentor support, and career skills that will increase their competitiveness for graduate training programs and advance their scientific and clinical career pathways. In doing so, this project will broaden the participation and foster the development of a cohort of future biomedical research scholars who themselves are committed to DEIA mentorship, and serve as a model that informs future development of culturally responsive training environments.
期刊论文(6)
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会议论文
DOI: 10.1371/journal.pgen.1010496
发表时间: 2022-11
期刊: PLoS genetics
影响因子: 4.5
作者: []
通讯作者:
DOI: 10.1007/s11914-023-00783-w
发表时间: 2023-04
期刊: Current osteoporosis reports
影响因子: 4.3
作者: []
通讯作者:
DOI: 10.1111/joa.13847
发表时间: 2023-03-01
期刊: JOURNAL OF ANATOMY
影响因子: 2.4
作者: [Diamond, Kelly M., Burtner, Abigail E., Maga, A. Murat]
通讯作者: Maga, A. Murat
Causal Genes at BMD Loci
  • 批准号:
    10163803
  • 项目类别:
  • 资助金额:
    $42.41万
  • 财政年份:
    2020
  • 负责人:
    Ronald Y Kwon
  • 依托单位:
Diversity Supplement for Ernesto Morfin Montes de Oca
  • 批准号:
    10172707
  • 项目类别:
  • 资助金额:
    $6.5万
  • 财政年份:
    2020
  • 负责人:
    Ronald Y Kwon
  • 依托单位:
Causal Genes at BMD Loci
  • 批准号:
    10424472
  • 项目类别:
  • 资助金额:
    $45.12万
  • 财政年份:
    2020
  • 负责人:
    Ronald Y Kwon
  • 依托单位:
Causal Genes at BMD Loci
  • 批准号:
    10415241
  • 项目类别:
  • 资助金额:
    $3.25万
  • 财政年份:
    2020
  • 负责人:
    Ronald Y Kwon
  • 依托单位:
海外基金