Clinical Core D

项目总结-临床和生物统计学核心D 德克萨斯州艾滋病研究发展中心（D-CFAR）位于贝勒医学院 （贝勒）和得克萨斯大学休斯顿健康科学中心（UTHealth）和得克萨斯生物医学中心 研究所（TxBiomed）在圣安东尼奥。战略规划过程表明需要临床和 生物统计学研究的支持，建立和早期阶段的研究人员在国内机构。 因此，德克萨斯州D-CFAR将建立临床和生物统计学核心（CBC，核心D）， 艾滋病毒研究人员和生物统计学家的资源和专业知识，以促进高影响力的临床，翻译， 和基础科学研究，旨在结束艾滋病毒和优化艾滋病毒健康在得克萨斯州。核心领导 团队在研究设计、临床研究、研究实施和数据方面具有丰富的经验 管理和分析。它还与国家生物库和储存库有很好的联系，因此， 能够接触和支持各种各样的调查人员。德克萨斯州D-CFAR调查人员和附属机构 用户，无论是初级或新的艾滋病毒研究或参与机构，可能缺乏知识，如何 设计、启动和实施研究;如何获得或访问临床样本或数据;和/或如何设计 并执行适当和可靠的数据管理和分析计划。CBC的目标是填补这一空白。到 这样做，核心D将为初级研究人员提供项目开发和实施服务 或艾滋病毒研究或D-CFAR机构的新成员;提供人体组织和血液样本， 临床、转化和基础科学研究;并提供数据分析、数据管理和 为HIV研究或D-CFAR的初级或新手研究者提供生物统计咨询服务 机构职能体系D-CFAR CBC将通过指导和招聘进行激励，并通过项目提供便利。 实施高影响力的研究，满足当前和预期的临床，转化和基础 当地研究人员、NIH和当地社区的科学研究和教育需求 有感染艾滋病毒的风险。核心领导层与D-CFAR领导层合作， 全面的行动计划、一套活动、政策和程序以及评估指标，以确保成功。 通过实现我们的目标，我们将朝着终结艾滋病毒和优化艾滋病毒健康的目标迈进， 德克萨斯州，并能够在5年内过渡到全面CFAR资金。

PROJECT SUMMARY – CLINICAL AND BIOSTATISTICS CORE D The Texas Developmental Center for AIDS Research (D-CFAR) is based at Baylor College of Medicine (Baylor) and University of Texas Health Science Center at Houston (UTHealth) and the Texas Biomedical Research Institute (TxBiomed) in San Antonio. A strategic planning process demonstrated need for clinical and biostatitistical research support among both established and early stage investigators at the home institutions. The Texas D-CFAR will therefore establish a Clinical and Biostatistics Core (CBC, Core D) to capiltalize on the resources and expertise of HIV investigators and biostatisticians to facilitate high-impact clinical, translational and basic science research aimed at Ending HIV and Optimizing HIV Health in Texas. The Core leadership team has extensive experience in study design, clinical research, and research implementation, and data management and analysis. It also is well connected with national biobanks and repositories and is thus positioned to reach and support a diverse array of investigators. Texas D-CFAR investigators and affiliated users, whether junior or new to HIV research or the participating institutions, may lack knowledge of how to design, initiate and implement studies; how to obtain or access clinical samples or data; and/or how to design and execute appropriate and reliable data management and analytic plans. The CBC goal is to fill that gap. To do this, Core D will provide project development and implementation services for investigators who are junior or new to HIV research or D-CFAR institutions; provide access to human tissue and blood samples, facilitating clinical, translational and basic science research; and provide data analysis, data management and consultative biostatistical services to investigators who are junior or new to HIV research or D-CFAR institutions. The D-CFAR CBC will stimulate through mentorship and recruitment and facilitate through project implementation high-impact research, meeting the current and anticipated clinical, translational and basic science research and educational needs of local investigators, the NIH and our local communities of people with and at risk for HIV. The Core leadership, in collaboration with the D-CFAR leadership, has identified a comprehensive action plan, set of activities, policies and procedures and evaluation metrics to ensure success. Through accomplishing our aims, we will move toward our goal of Ending HIV and Optimizing HIV Health in Texas and be able to transition to full CFAR funding in 5 years.