Postdoctoral Research Training in Alzheimer's Disease and Related Neurodegenerative Disorders

这是一项更新纽约大学格罗斯曼医学院专注于阿尔茨海默病和相关神经退行性疾病的高级博士后培训计划的提案。迫切需要培训早期职业科学家，他们将研究阿尔茨海默氏症和相关的神经退行性疾病，开发新的干预措施，并将这些发现从工作台到床边，从床边到社区。该项目将继续设在认知神经学中心，这是一个旨在促进合作研究的跨部门、多学科项目，有37名教职员工担任导师。该计划的目标是赋予具有不同科学背景的受训者必要的技能、多学科方法和严格的方法，以推动阿尔茨海默病和相关神经退行性疾病领域的发展。这一续签申请通过任命杰出的认知神经学临床科学家研究人员来扩展我们目前的培训计划。我们将在我们之前的培训计划的基础上，从一批合格的医学博士、医学博士和博士申请者中任命三名博士后实习生和一名认知神经学研究员。根据美国国立卫生研究院关于博士后研究培训的建议，受训人员的任期为两年，并将在随后的几年中继续接受指导和职业发展支持。该计划培训这些研究员的目标将通过量身定制的课程来实现，其中包括严格的研究技术和定量分析培训、加强指导、基础概念教学、磨练科学交流技能和职业规划。这一培训计划使博士后研究员能够为现代研究的高度协作和跨学科性质做好准备，方法是：(A)在阿尔茨海默病和相关神经退行性疾病、临床方法、统计分析和严格的实验设计领域提供高质量的科学培训；(B)加强指导，帮助学员在未来的科学职业生涯中取得进展；以及(C)培训学术研究成功所必需的专业技能，包括批判性阅读、拨款撰写、口头陈述、领导力、管理和网络。培训下一代具有阿尔茨海默氏症和相关神经退行性疾病专业知识的研究和临床科学家是，并将在未来多年继续是美国公共卫生的优先事项。我们的协作T32计划支持这些早期科学家在这个关键领域开始他们独立而成功的职业生涯。

This is a proposal to renew an advanced postdoctoral training program focused on Alzheimer’s disease and related neurodegenerative disorders at NYU Grossman School of Medicine. There is a critical need to train early career scientists who will investigate Alzheimer’s disease and related neurodegenerative disorders, develop new interventions, and translate these findings from bench to bedside and from bedside to community. The program will continue to be housed in the Center for Cognitive Neurology, an extra-departmental, multidisciplinary program designed to foster collaborative research, with 37 faculty members serving as mentors. The goal of the program is to endow trainees with diverse scientific backgrounds with the necessary skills, multidisciplinary approaches, and rigorous methodologies to advance the field of Alzheimer’s disease and related neurodegenerative disorders. This renewal application expands our current training program by appointing exceptional cognitive neurology clinician-scientist researchers. We will build on our previous training program by appointing three postdoctoral trainees and one cognitive neurology fellow from a well-qualified pool of MD, MD/PhD, and PhD applicants. As per the NIH recommendation for postdoctoral research training, the trainees will be appointed for two years and will continue to receive mentoring and career development support in subsequent years. The program's goals to train these fellows will be accomplished through a tailored curriculum that includes training in rigorous research techniques and quantitative analysis, enhanced mentorship, didactics in foundational concepts, honing science communication skills, and career planning. This training program enables postdoctoral fellows to prepare for the intensely collaborative and interdisciplinary nature of modern research by providing: (a) high-quality scientific training in the area of Alzheimer’s disease and related neurodegenerative disorders, clinical approaches, statistical analyses, and rigorous experimental design; (b) enhanced mentoring that aids trainees’ progress toward future careers in science, and (c) training in the professional skills that are necessary for success in academic research, including critical reading, grant writing, oral presentation, leadership, management, and networking. The training of the next generation of research and clinician scientists with expertise in Alzheimer’s disease and related neurodegenerative disorders is, and will remain, a public health priority in the United States for many years to come. Our collaborative T32 program supports these early scientists as they launch their independent and successful careers in this critical field.