HEAL Data2Action Modeling and Economic Resource Center

Hear Data2Action(D2a)计划是一项协调努力，旨在促进合成和现实世界 应用现有数据指导和监测服务提供的改进，以预防或治疗阿片类药物的使用 混乱(OUD)和痛苦。总的来说，这些项目将弥补在提供循证证据方面的差距。 卫生与公众服务部药物过量预防战略四大支柱的实践：初级预防、危害 减少、治疗阿片类药物使用障碍和康复支持。HERE D2A建模与经济性 资源中心(MERC)将通过提供模拟方面的专业知识来支持Hear D2A创新项目 建模和经济评估方法，并将就以下问题与Hear D2A创新资助获得者进行磋商 在其当地实施活动中应用这些方法和见解。商业委员会还将进行 原创性研究应用最先进的经济和模拟建模专业知识来理解和 解决吸毒过量的危机。自2015年以来，我们一直通力合作，领导着一个非常成功的多 机构NIDA资助的国家卓越中心，治疗健康经济学中心 对物质使用障碍、丙型肝炎病毒和艾滋病毒的干预(珍视)。因此，我们是唯一有资格领导 Hear D2A Merc的目标如下：1)通过以下方式支持Hear D2A创新项目 关于严格建模技术、成本分析和行为的应用的方法论咨询 支持项目选择和实施循证做法的经济战略 满足服务交付需求；2)开发可供创新项目使用的工具，以使 关于不同利益攸关方不同执行干预措施的相对成本的知情决定， 衡量这些努力的总成本，并向设计适当的支付系统提供信息 支持可持续性；3)使用元建模技术开发用户友好的界面，以便 为一个系统或社区生成的仿真模型结果可适用于其他系统或社区 系统/社区或在当地情况变化时进行调整；4)利用 高级建模和卫生经济学方法，以现有数据为基础，提供对 通过战略实施循证医学解决吸毒过量危机的复杂动力 练习。Hear D2AMerc将支持将卫生经济学和建模研究应用于 关于预防或治疗阿片类药物使用障碍和疼痛的服务的现实世界决策，将进一步科学 该领域的创新，并将建立一个将卫生经济学和建模整合到 系统一级的药物使用、治疗和预防政策。Hear D2AMerc将会是 与Hear D2A研究采用支持中心(RASC)的工作协作，包括 协商和执行支助核心的措施和工具目录，并将利用 为Hear D2A数据基础架构支持中心(DISC)的资源做出贡献。

The HEAL Data2Action (D2A) Program is a coordinated effort to promote the synthesis and real-world application of existing data to guide and monitor improvements in service delivery to prevent or treat opioid use disorder (OUD) and pain. Collectively, these projects will address gaps in the delivery of evidence-based practices in each of the four pillars of the HHS Overdose Prevention Strategy: primary prevention, harm reduction, treatment of opioid use disorder, and recovery support. The HEAL D2A Modeling and Economic Resource Center (MERC) will support the HEAL D2A Innovation Projects by providing expertise in simulation modeling and economic evaluation methods and will consult with the HEAL D2A Innovation Grant recipients on applying these methods and insights in their local implementation activities. The MERC will also conduct original research applying state-of-the-art economic and simulation modeling expertise to understand and address the overdose crisis. Since 2015, we have worked collaboratively to lead a highly successful multi- institutional NIDA-funded national center of excellence, the Center for Health Economics of Treatment Interventions for Substance Use Disorder, HCV, and HIV (CHERISH). We are thus uniquely qualified to lead the HEAL D2A MERC with the following aims: 1) to support the HEAL D2A Innovation Projects by providing methodological consultation on the application of rigorous modeling techniques, cost analyses, and behavioral economic strategies to support the projects' selection and implementation of evidence-based practices to address service delivery needs; 2) to develop tools that can be readily used by the Innovation Projects to make informed decisions about the relative costs of different implementation interventions to different stakeholders, to measure the overall costs of these efforts, and to inform the design of appropriate payment systems that support sustainability; 3) to use meta-modeling techniques to develop a user-friendly interface so that simulation model results generated for one system or community can be adapted for other systems/communities or adapted when local circumstances change; 4) to conduct novel research using advanced modeling and health economics approaches that build on existing data to provide insights into the complex dynamics of addressing the overdose crisis through strategic implementation of evidence-based practices. The HEAL D2A MERC will support the application of health economics and modeling research to real-world decision making about services to prevent or treat opioid use disorder and pain, will further scientific innovation in the field, and will establish a paradigm for integrating health economics and modeling into substance use treatment and prevention policies at the system level. The HEAL D2A MERC will be collaborative with the work of the HEAL D2A Research Adoption Support Center (RASC), including the consultations and catalog of measures and tools of the Implementation Support Cores, and will leverage and contribute to the resources of the HEAL D2A Data Infrastructure Support Center (DISC).