Novel MRI approaches to map focal cortical dysplasia in focal epilepsy

局灶性皮质发育不良(FCD)是局灶性癫痫的常见原因，对药物具有抵抗力。如果能够明确识别，手术切除可以治愈癫痫，但需要更好的检测和定位FCD的方法，因为标准成像技术在30%的患者中是阴性的。在这个项目中，我们计划开发新的MRI方法来诊断FCD，从而为有可能接受手术的局灶性癫痫患者创造一个新的基于MRI的诊断工具。

Focal cortical dysplasia (FCD) is a common cause of focal epilepsy that is resistant to medication. When it can be identified clearly, surgical removal can cure the epilepsy but better methods of detecting and mapping FCD are required because standard imaging techniques are negative in 30% of patients. In this project, we plan to develop new MRI methods to diagnose FCD, thereby creating a new MRI-based diagnostic tool for patients with focal epilepsy who are potential surgical candidates.