Priming the Pump: Training Physician-Scientists in Translational Psychiatry

项目总结 该提案旨在继续和改进住院医师培训研究轨道，明确目标是 招聘在研究方面有良好记录的医学博士和医学毕业生。该计划提供 早期接触精神病学的临床研究，以激发我们的基础研究人员对翻译研究的兴趣 理科实习生。此外，研究轨道居民有14.5个月的保护时间为独立 研究项目。这几个月通过密集的指导来增加，由PI监督，发挥以下作用 “元导师”，以及侧重于伦理学、统计学、研究设计和原理的定制课程 翻译研究的成果。所有这些都是在满足ACGME临床培训要求的同时实现的，因此 毕业生在精神病学方面具有董事会资格。这种方法是为了弥补目前的状况。 其中，医学博士/博士在因临床需要而中断后，经常面临重新开始他们的研究的问题。 训练。我们已经有初步证据表明，我们为期4年的计划允许研究轨道居民“快速启动” 他们的研究生涯，使他们为研究奖学金和K奖过程做好了更好的准备， 最终为他们成为成功的独立调查人员奠定了基础。作为一个额外的奖励，培训 由研究跟踪计划建立的基础设施为以下项目提供了多个入口点的机会 没有以前研究经验的居民探索研究和发展基本研究技能。通过这件事 我们预计将加强准备进行转化性研究的内科科学家的渠道 在精神病学中，NIMH的一个关键目标。

PROJECT SUMMARY This proposal aims to continue and improve upon a residency training research track with the explicit goal of recruiting MD/PhD and medical graduates with a track record in conducting research. The program provides early exposure to clinical research in psychiatry to stimulate interest in translational research among our basic science trainees. In addition, research track residents have 14.5 months of protected time for an independent research project. These months are augmented by intensive mentoring, overseen by the PIs, functioning as “meta-mentors,” as well as a customized curriculum focused on ethics, statistics, research design, and principles of translational research. All this is attained while meeting ACGME clinical training requirements so that graduates are board-eligible in psychiatry. This approach is intended to remedy the current state of affairs wherein MD/PhDs often are faced with “re-starting” their research after a hiatus created by the need for clinical training. We already have early evidence that our 4-year program permits research track residents to “jump start” their research career, rendering them better prepared for research fellowships and the K-award process, ultimately setting them up for successful careers as independent investigators. As an added bonus, the training infrastructure established by the research track program provides an opportunity for multiple “on-ramps” for residents without prior research experience to explore research and develop basic research skills. Through this program we anticipate enhancing the pipeline of physician-scientists prepared to conduct translational research in psychiatry, a key goal of the NIMH.