Neural Injury & Plasticity

项目摘要/摘要 这是一份竞争续签神经损伤和医疗机构培训补助金的申请。 塑性(NIP)。我们请求支持4名高级博士后，他们将在研究方面接受培训 神经损伤和恢复中心(CNIR)教职员工的神经损伤和可塑性 乔治城大学。本培训计划的目的是为科学家研究基础知识做好准备。 通过创伤或神经退行性变过程造成的神经损伤的机制，并了解基本机制 神经可塑性对神经损伤后的修复过程可能是有益的。我们的目标是 培养有能力并致力于更深入地理解神经反应的研究人员 损伤和可塑性。一个经验丰富、资金雄厚的团队，由20名教职员工组成，他们从事一系列研究 对神经损伤和可塑性的兴趣和专业知识将参加这个培训计划。大多数学生都会 通过乔治城大学神经科学跨学科项目(IPN)进入研究生院。在……里面 头两年，他们将参加课程作业，并轮流在潜在导师的实验室中轮换。那些 对NIP计划感兴趣的人将参加一个或多个具体相关的课程，并开始参加 NIP日志俱乐部。在第二年，学生将正式申请NIP培训计划的大纲 由NIP培训学院的潜在导师或共同导师批准的论文研究提案。AS NIP学员将参加NIP特定培训，培训内容包括：实验设计和统计 方法讲习班(4x年)；公平数据讲习班(数据管理和无偏分析；4x年)； 每月会议的重点是深入讨论神经障碍/神经损伤的具体方面和 可塑性(实习生与教员专家配对)；每周NIP杂志俱乐部和关于严谨性的扩展讨论， 综合推理和统计素养培训；专业发展培训(即电梯推介、 授予写作和演示技能、有效沟通技能、境内流离失所者、职业机会)。实习生将 在每年的学生研讨会上报告他们的研究结果，在全国会议上发表演讲，以及 在同行评议的期刊上发表文章。在公共卫生方面，该计划将培养一支 神经科学家接受了研究和/或研究项目管理的培训，通过这些项目，新的和更多的 可以开发出治疗急性和退行性神经系统疾病的有效方法。

Project Summary/Abstract This is an application for the competitive renewal of an Institutional Training Grant in Neural Injury and Plasticity (NIP). We request support for 4 advanced predoctoral students who will be trained in research on neural injury and plasticity by faculty participating in the Center for Neural Injury and Recovery (CNIR) at Georgetown University. The purpose of this training program is to prepare scientists to investigate fundamental mechanisms of neural injury, by trauma or neurodegenerative processes and to understand basic mechanisms of neural plasticity that may be functionally beneficial to the repair processes after neural injury. Our goal is to train researchers who will be capable of and committed to a deeper understanding of responses to neural injury and plasticity. An experienced and well-funded group of 20 faculty members with a range of research interests and expertise in neural injury and plasticity will participate in this training program. Most students will enter graduate school through the Georgetown University Interdisciplinary Program in Neuroscience (IPN). In the first two years they will take course work and rotate through the laboratories of potential mentors. Those interested in the NIP Program will take one or more specifically relevant courses and begin to participate in the NIP Journal Club. In the second year, students will formally apply to the NIP Training Program with the outline of a thesis research proposal approved by a potential mentor or co-mentors from the NIP Training Faculty. As NIP Trainees they will participate in NIP Specific Training which includes: Experimental Design & Statistical Methodology Workshops (4x’s year); FAIR data Workshops (data curation & unbiased analyses; 4x’s year); monthly meetings focused on in-depth discussions of neurodisorders/aspects specific to neural injury and plasticity (trainee’s paired with faculty experts); weekly NIP Journal Club and extended discussions on rigor, integrative reasoning and statistical literacy training; professional development training (i.e., elevator pitches, grant writing and presentation skills, effective communication skills, IDPs, career opportunities). Trainees will report results from their research in yearly student seminars, presentations at national meetings, and as publications in peer-reviewed journals. With respect to public health, this program will create a cadre of neuroscientists trained for research and/or management of research programs, through which new and more effective treatments for acute and degenerative disorders of the nervous system can develop.