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中文摘要
翻译
项目总结/摘要(实验辐照共享资源) 实验辐照共享资源(EI-SR)提供最先进的设备和专家 Rogel癌症中心(Rogel)成员进行放射治疗研究,主要是在小鼠 以及大鼠模型和细胞系。这一特别报告员于1991年首次设立,一直得到下列机构的批准和资助: 自NCI CCSG成立以来,在上一次CCSG更新时,EI-SR获得了“优秀”的绩效评级。 EI-SR董事和常务董事的经验和专业知识为Rogel调查人员提供了信息 剂量和治疗方案,特别是在动物研究中,并了解标准临床 放射治疗,以确保以最佳方式使用实验资源。EI-SR服务对Rogel至关重要 对放射生物学和放射治疗感兴趣的成员,以及那些将放射作为 研究工具。
英文摘要
PROJECT SUMMARY/ABSTRACT (EXPERIMENTAL IRRADIATION SHARED RESOURCE) The Experimental Irradiation Shared Resource (EI-SR) provides access to state-of-the-art equipment and expert consultation for Rogel Cancer Center (Rogel) members undertaking radiation therapy studies primarily in mouse and rat models and cell lines. First established in 1991, this SR has been approved and funded continuously by the NCI CCSG since its inception. At the last CCSG renewal, the EI-SR received a merit rating of “Outstanding.” The experience and expertise of the EI-SR Director and Managing Director offer Rogel investigators information on dosage and treatment regimens, particularly in animal studies and with a knowledge of standard clinical radiotherapy, to ensure experimental resources are used in an optimal way. EI-SR services are critical to Rogel members interested in radiation biology and radiation therapy, as well as those for whom radiation serves as a research tool.
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Project 1: Combining PARP inhibition with radiation to sensitize HR proficient pancreatic cancers to immunotherapy
Targeting the DNA damage response in combination with radiation to induce innate immunity and improve immunotherapy efficacy in pancreatic cancer
Targeting the DNA damage response in combination with radiation to induce innate immunity and improve immunotherapy efficacy in pancreatic cancer
Selective Sensitization of Pancreatic Cancer to Therapy by Chk1 and PARP1 Inhibit
国内基金
海外基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
  • 批准号:
    2021JJ40433
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2021
  • 负责人:
    孙磊
  • 依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
  • 批准号:
    32001603
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2020
  • 负责人:
    段真珍
  • 依托单位:
AREA国际经济模型的移植.改进和应用
  • 批准号:
    18870435
  • 项目类别:
    面上项目
  • 资助金额:
    2.0万元
  • 批准年份:
    1988
  • 负责人:
    史树中
  • 依托单位: