Behavioral Parenting Skills as a Novel Target for Improving Pediatric Medication Adherence

摘要 该补助金的父母补助金（R 01 CA 258337 - 01 A1）侧重于养育子女与 在被诊断为急性淋巴细胞白血病（ALL）的幼儿中， 最常见的儿科癌症父母的任务是每天给口服化疗药物， 家庭，这种经历的特点是亲子冲突、后勤困难和痛苦。为了 制定干预措施，以尽量减少成功给药的障碍，关键是要了解 父母的技能，行为和经验，给儿科癌症患者在家里的药物。之一 这项由家长资助的研究的目的是通过视频直接观察药物管理 在家中进行记录，以收集客观数据，以描述日常的具体育儿经验。 以及影响幼儿用药的发作水平。对录像记录的 直接观察家长管理药物指出，有机会增加现有的 定量编码方案与新开发的定性编码方案。候选人 补充将受益于机会，以扩大她现有的研究专长，在传播科学， 创建一个定性编码方案，捕获有关药物管理的细微差别的上下文数据， 家庭环境。该补充的候选人还将通过分析 父母的社会人口学数据和药物管理之间的关联，以确定 药物依从性结果的潜在差异模式，从而有助于她的目标， 她在差异研究方面的经验。最后，为了实现候选人拓宽她的目标， 在健康素养的专业知识，她将扩大家长项目的目标，考虑家长健康素养作为一个 通过对健康素养进行额外分析， 变量，以确定与父母照顾者的社会人口特征的潜在关联。的结果 这些活动将填补有关可改变因素（照顾者行为和健康素养）的知识空白 技能），可以通过有针对性的干预措施来解决，以改善患者的结果和减轻差异。

Abstract This parent grant (R01CA258337-01A1) for this supplement focuses on the relationship between parenting skills and medication adherence in young children diagnosed with acute lymphoblastic leukemia (ALL), the most common pediatric cancer. Parents are tasked with giving daily medications for oral chemotherapy at home, an experience that can be marked by parent-child conflict, logistical difficulties, and distress. In order to develop an intervention to minimize barriers to successful medication administration, it is critical to understand parental skills, behaviors, and experiences with giving pediatric cancer patients medication at-home. One of the aims of this parent grant-funded study uses direct observation of medication administration via video recording in the home to collect objective data to characterize the specific parenting experiences at the daily and episode levels that shape medication administration in young children. Initial reviews of video-recorded direct observations of parents administering medications point to an opportunity to augment the existing quantitative coding schemes with newly developed qualitative coding schemes. The candidate for this supplement will benefit from the opportunity to expand her existing research expertise in caregiving science by creating a qualitative coding scheme that captures nuanced contextual data about medication administration in the home setting. The candidate for this supplement will also build on the parent project by analyzing associations between parents' sociodemographic data and medication administration in order to identify potential patterns of disparities in medication adherence outcomes, thus contributing to her goal to strengthen her experience in disparities research. Finally, in order to fulfill the candidate's goal of broadening her expertise in health literacy, she will extend the parent project's aim of considering parental health literacy as a potential correlate of medication adherence experiences by conducting additional analysis of the health literacy variable to identify potential associations with parental caregiver's sociodemographic traits. Findings from these activities will fill gaps in knowledge about modifiable factors (caregiver behaviors and health literacy skills) that can be addressed via targeted interventions to improve patient outcomes and mitigate disparities.