University of Colorado Cancer Center Support Grant - ESSP Supplement - C Stewart

摘要 科罗拉多大学癌症中心(UCCC)推动癌症发现和创新，翻译如下 将发现转化为临床，引领以患者为中心的护理，减少健康差距，培训下一代 专注于癌症的科学家，并努力优化对我们的集水区-科罗拉多州的影响。 UCCC受益于慷慨的资金增加，并对所有项目进行了大量投资 和结构。最近进展的重点包括：1)完成和部署一个全面的 战略计划；2)方案的重组；3)招聘有活力和有成就的新领导人，包括 一名董事(舒利克)和一名第二副主任(布拉德利)，并征聘首任副主任 社区外联和参与以及信息学和数据科学；4)建立两个 癌症与老龄化和癌症与新陈代谢的交叉主题；以及5)全面改革UCCC成员资格 标准，以更好地集中成员的活动，并加强对指导的重视。这一大笔输液 资源和结构调整更好地促进了实验室的多项创新发现 通过研究人员发起的试验、FDA的批准和建立新的护理标准，将药物转移到床边。 它们还成功地实现了双向社区外展和参与以及以人口为基础 流域内的方案，继续侧重于增加包容性和多样性。物理空间， 组织能力、跨学科协作和协调、癌症重点和机构 所有资源都得到了改善，使UCCC在未来走上了成功的轨道。在下一个 在资助期内，UCCC将重点关注战略目标、目标以及 战略规划。这些战略的重点包括努力：1)提供卓越的研究基础设施 和最先进的资源共享；2)扩大临床研究、临床试验和研究者发起的试验； 3)扩展跨项目的研究和干预措施，以解决健康结果、差异和服务不足问题 人群；4)培养未来肿瘤学研究人员、临床医生和管理人员的渠道； 加强UCCC内部和所有地点的结盟和合作；以及5)增加慈善支持。 如有必要，UCCC领导层将修改课程以适应意外挑战(例如，COVID)和 机会(例如，建立数据科学的校园计划)。

ABSTRACT The University of Colorado Cancer Center (UCCC) drives cancer discovery and innovation, translates these findings to the clinic, leads in patient-centered care, reduces health disparities, trains the next generation of cancer focused scientists, and strives to optimize the impact on our catchment area – the State of Colorado. UCCC has benefited from a generous increase in funding and has made significant investments into all programs and structures. The highlights of recent progress include: 1) completion and deployment of a comprehensive strategic plan; 2) restructure of the programs; 3) recruitment of dynamic and accomplished new leaders including a Director (Schulick) and a second Deputy Director (Bradley), and recruitment of inaugural Associate Directors of Community Outreach and Engagement, as well as Informatics and Data Science; 4) establishment of two cross cutting themes of Cancer and Aging and Cancer and Metabolism; and 5) overhaul of UCCC membership criteria to better focus the activities of members and to increase emphasis on mentoring. This large infusion of resources and restructuring have better enabled multiple innovative discoveries in the laboratories to be brought to the bedside through investigator-initiated trials, FDA approval, and establishment of new standards of care. They have also enabled successful bi-directional community outreach and engagement and population-based programs within the catchment, with continued focus on increasing inclusion and diversity. The physical space, organizational capabilities, transdisciplinary collaboration and coordination, cancer focus, and institutional resources have all been improved, setting UCCC on a trajectory of success well into the future. In the next funding period, UCCC will focus on the strategic aims, goals, as well as the 21 specific strategies outlined in the strategic plan. Highlights of these strategies include efforts to: 1) provide outstanding research infrastructure and state-of the art shared resources; 2) expand clinical research, clinical trials and investigator-initiated trials; 3) expand research and interventions across programs to address health outcomes, disparities, and underserved populations; 4) nurture the pipeline of prospective oncology researchers, clinicians, and administrators; strengthen alignment and collaboration within the UCCC and across all sites; and 5) grow philanthropic support. As necessary, UCCC leadership will modify the course to adjust to unexpected challenges (e.g., COVID) and opportunities (e.g., campus-wide initiative to build data science).