Technology-based intervention for alcohol-related sexual risk behaviors in young women with sexual victimization histories

这一独立之路奖的长期目标有两个：(1)支持候选人布莱尼博士 建立一个独立的研究项目，(2)促进她从博士后研究员过渡到 独立学院研究员。到目前为止，布莱尼博士的研究主要集中在 对年轻人的性侵害的后果，包括与以下方面有关的社会和性背景 性侵害风险。作为博士后培训的一部分，布莱尼博士的工作已经开始检查 酒精对有和无性侵害的年轻女性性风险模式的近似性影响 历史。布莱尼博士试图将她的培训从基础酒精研究扩展到开发和测试简介， 以技术为基础的干预措施，以减少酒精和性风险。这一长期目标将会实现 通过五年培训计划，包括精心挑选的指导团队以及有针对性的课程工作 (例如，课程、研讨会、讲习班)和实践培训经验。拟议研究的目标是 开发和测试一种专门的基于网络的干预措施，以减少与酒精有关的性行为风险 在有性侵害史的年轻女性中，这是一个高风险和未得到充分服务的群体。在.期间 指导阶段(K99)，干预将以用户为中心设计(Aim 1)，这是一个创新的 技术部门将目标人口纳入发展的所有阶段的方法。在……里面 目标1a，将起草干预内容并向目标人群(即 性侵害历史)以获取用户反馈。在目标1b中，干预设计将使用RAPID进行评估 在对干预进行编程之前，对用户反馈进行原型设计。一旦编程完成，Aim 1c将涉及 对目标人群进行干预交付的可用性测试。随着干预措施的发展，目标2 将通过基于网络的公开试验评估干预的可行性和可接受性。在独立阶段 (R00)，将进行基于网络的随机对照试验，以测试干预效果(目标3a)、改变机制(Aim 3b)和潜在的主持人(目标3c)。调查结果将作为NIAAA R01提交期间的试点数据 R00阶段。该应用程序的培训计划将重点放在干预开发和测试上， 创新方法，加强以技术为基础的干预开发，并先进统计。导师 (George，Bedard-Gilligan，Cue Davis，Rhew博士)和顾问(Billings，Widman博士)致力于 候选人的培训，每个人都将为研究和培训计划提供独特的专业知识。来自这一点的支持 获奖对候选人作为一名独立科学家的发展至关重要，他们可以为 通过开发和测试以技术为基础的干预措施来减少酒精和性风险，从而进行酒精研究。 华盛顿大学非常适合提供一流的培训经验，并将促进NIH的 使命是培养能够在长期研究资金方面具有竞争力的早期研究人员。

The long-term objective of this Pathway to Independence Award is two-fold: (1) support candidate Dr. Blayney in building an independent research program and (2) facilitate her transition from postdoctoral fellow to independent faculty researcher. To date, Dr. Blayney's research has focused on the risks for and consequences of sexual victimization in young adults, including the social and sexual contexts associated with sexual victimization risk. As part of postdoctoral training, Dr. Blayney's work has begun to examine the proximal influence of alcohol in sexual risk patterns for young women with and without sexual victimization histories. Dr. Blayney seeks to expand her training from basic alcohol research to developing and testing brief, technology-based interventions to reduce alcohol and sexual risk. This long-term objective will be achieved through a five-year training plan involving a carefully selected mentor team as well as targeted coursework (e.g., classes, seminars, workshops) and hands-on training experiences. The goal of the proposed research is to develop and test a specialized web-based intervention to reduce alcohol-related sexual risk behaviors among young women with sexual victimization histories, a high-risk and underserved group. During the mentored phase (K99), the intervention will be developed with user centered design (Aim 1), an innovative approach from the technology sector that incorporates the target population into all stages of development. In Aim 1a, intervention content will be drafted and presented to the target population (i.e., young women with sexual victimization histories) for user feedback. In Aim 1b, intervention design will be evaluated using rapid prototyping for user feedback before the intervention is programed. Once programed, Aim 1c will involve usability testing of intervention delivery with the target population. Following intervention development, Aim 2 will assess intervention feasibility and acceptability with a web-based open trial. During the independent phase (R00), a web-based RCT will be conducted to test intervention efficacy (Aim 3a), mechanisms of change (Aim 3b), and potential moderators (Aim 3c). Findings will serve as pilot data for an NIAAA R01 submission during the R00 phase. The training plan for this application will focus on intervention development and testing, innovative methods to enhance technology-based intervention development, and advanced statistics. Mentors (Drs. George, Bedard-Gilligan, Cue Davis, Rhew) and consultants (Drs. Billings, Widman) are committed to the candidate's training and each will provide unique expertise to the research and training plan. Support from this award will be essential to the candidate's development as an independent scientist who can contribute to alcohol research by developing and testing technology-based interventions to reduce alcohol and sexual risk. The University of Washington is well suited to provide a stellar training experience and will promote NIH's mission to develop early investigators who can be competitive for long-term research funding.