Reducing the chasm in behavioral health care for older adults with cancer: Development of the Center for Implementation Research in Cancer in Later Life (CIRCL)

项目摘要 老年癌症患者（OAC）占癌症患者和幸存者的比例很大且不断增长。 许多OAC的行为健康需求未得到满足，对他们的生活质量产生了重大的负面影响， 身体健康，以及对癌症护理的坚持和康复。有效的干预措施来解决这些问题 需求已经得到发展，但它们在癌症护理中的实施有限。传播和 实施（D&I）研究可以通过创建可实施的干预措施和确定 将这些干预措施纳入常规癌症护理的策略。可用的D&I研究基础设施是 由于缺乏针对人口和项目特定需求的定制、注重学员和早期职业生涯而受到限制 资源不足，无法满足当前的需求。拟议的项目解决了这些限制 通过开发新的跨学科研究基础设施，癌症实施研究中心 在以后的生活（CIRCL），将注入D&I研究方法到新的和现有的项目在所有阶段， OAC的行为干预发展。CIRCL将由行政、培训和研究部门组成 丹行政核心将提供专家领导、支持和监督，以确保 完成了CIRCL的使命和目标。该核心将由一个执行委员会组成， 行政支持团队、外部咨询理事会、OAC和护理者理事会。培训核心 将提供资源和网络机会，培训研究人员将D&I科学方法融入 他们的研究包括一个网络研讨会系列，正在进行的网络研讨会，导师计划和资源库。 研究核心的目的是评估研究者的研究需求，并提供资源， 促进对OAC行为干预的D&I研究。核心将管理一个国家 研究需求评估，为CIRCL资源的结构和内容提供信息，并将支持试点项目 奖励计划和年度研究会议。项目的总体目标将在两个方面实现。 阶段。在R21阶段（第1-2年），将开发CIRCL的核心组件，包括招聘 行政人员，启动CIRCL网站，建立咨询和OAC和照顾者委员会， 管理研究需求评估，并为所有CIRCL制定标准操作程序 活动在R33阶段（3-5年），我们将利用这一已建立的基础设施来培训研究人员 支持D&I研究项目。通过CIRCL提供的资源将在全国范围内进行宣传， 有针对性地与代表性不足群体的调查人员进行外联，以增加研究人员队伍的多样性。 R21阶段的基准评估将确保CIRCL资源及时开发， 为R33阶段做准备。R33阶段的评估将评估CIRCL资源的利用情况， 这些资源对D&I研究对OAC行为干预的影响。

PROJECT SUMMARY Older adults with cancer (OACs) comprise a large and growing proportion of cancer patients and survivors. Many OACs have unmet behavioral health needs with significant negative implications for their quality of life, physical health, and adherence to and recovery from cancer care. Efficacious interventions to address these needs have been developed but their implementation into cancer care is limited. Dissemination and implementation (D&I) research can address this gap by creating implementable interventions and identifying strategies for integrating these interventions into routine cancer care. Available D&I research infrastructure is limited by a lack of tailoring to population and project-specific needs, a focus on trainees and early career faculty, and insufficient resources to meet current demand. The proposed project addresses these limitations by developing new interdisciplinary research infrastructure, the Center for Implementation Research in Cancer in Later Life (CIRCL) that will infuse D&I research methods into new and existing projects across all stages of behavioral intervention development for OACs. CIRCL will consist of Administrative, Training, and Research Cores. The Administrative Core will provide expert leadership, support, and oversight to ensure that the mission and aims of CIRCL are accomplished. The Core will consist of an Executive Committee, administrative Support Team, external Advisory Council, and OAC and Caregiver Council. The Training Core will provide resources and networking opportunities to train investigators to integrate D&I science methods into their research including a webinar series, work-in-progress webinar, mentorship program, and resource library. The purpose of the Research Core is to evaluate the research needs of investigators and provide resources to facilitate research on the D&I of behavioral interventions for OACs. The Core will administer a national research needs assessment to inform the structure and content of CIRCL resources and will support a pilot awards program and annual research conference. The overall project objectives will be met across two phases. During the R21 phase (years 1-2), core components of CIRCL will be developed including hiring administrative staff, launching the CIRCL website, establishing the Advisory and OAC and Caregiver Councils, administering the research needs assessment, and developing standard operating procedures for all CIRCL activities. During the R33 phase (years 3-5), we will utilize this established infrastructure to train researchers and support D&I research projects. The resources available through CIRCL will be advertised nationally with targeted outreach to investigators in underrepresented groups to increase diversity in the research workforce. Benchmark evaluation during the R21 phase will ensure CIRCL resources are developed in a timely manner in preparation for the R33 phase. Evaluation of the R33 phase will assess utilization of CIRCL resources and the impact of those resources on the advancement of D&I research on behavioral interventions for OACs.