Reagents for Immunologic Analysis of Under-represented Mammalian Models

Integral Molecular提出了一个针对免疫细胞标志物的泛反应性单克隆抗体（mAb）的大面板，用于 在九种代表性不足的哺乳动物模型中进行免疫功能和反应的研究。由于某些哺乳动物模型显示出人类免疫的许多特征，但由于缺乏免疫试剂而同样未被充分利用，因此开发交叉反应抗体以研究几种动物物种中的免疫应答将影响对几种人类疾病的理解。

Integral Molecular proposes to generate a large panel of pan-reactive monoclonal antibodies (mAbs) against immune cell markers to be used in studies of immune function and responses in nine underrepresented mammalian models. Since certain mammalian models display many features of human immunity but are similarly underutilized due to lack of immunologic reagents, development of cross-reacting antibodies to study immune responses in several animal species will impact the understanding of several human diseases.