Epitope-directed monoclonal antibody production for mosquito immune cells (for malaria)
Epitope-directed monoclonal antibody production for mosquito immune cells (for malaria)
批准号:
10933280
负责人:
YANG YU
金额:
$60.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-09-01 至 2025-08-31
关键词:
AntibodiesAntigensCellsCellular ImmunityCulicidaeEpitopesHemocytesHumanHumoral ImmunitiesImmuneImmune responseImmunoassayMalariaMediatingMonoclonal AntibodiesProteinsResearchSurface Plasmon ResonanceValidationVector-transmitted infectious diseasebiomarker identificationdisease transmissionmonoclonal antibody productionpathogen
中文摘要
Luna Labs提出开发单克隆抗体(mAb),用于识别和表征蚊子免疫细胞,通过各种免疫测定和表面等离子体共振(SRP)进行免疫应答和验证。由于该项目的重点是蚊子血细胞中表达的介导对病原体的先天性细胞和体液免疫的靶蛋白,所产生的抗体将促进对蚊子传播的人类媒介传播疾病的研究。
英文摘要
Luna Labs proposes to develop monoclonal antibodies (mAbs) for use in the identification and characterization of mosquito immune cells for immune responses and validation through various immunoassays and surface plasmon resonance (SRP). Since the project focuses on target proteins expressed in mosquito hemocytes that mediate innate cellular and humoral immunity to pathogens, and the antibodies produced will promote the research on human vector-borne diseases transmitted by mosquitoes.
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国内基金
海外基金
Neo-antigens暴露对肾移植术后体液性排斥反应的影响及其机制研究
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批准号:2022J011295
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项目类别:省市级项目
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资助金额:10.0万元
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批准年份:2022
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负责人:王亚伟
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依托单位:
结核分枝杆菌持续感染期抗原(latency antigens)的重组BCG疫苗研究
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批准号:30801055
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项目类别:青年科学基金项目
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资助金额:19.0万元
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批准年份:2008
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负责人:王丽梅
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依托单位: