CORE--ANIMAL RESOURCE AND CLINICAL CORE

动物和临床中心将负责执行所有 研究中所有动物的外科手术和术后护理， 以及用于制备、施用和监测 猴子保持高胆固醇饮食。 核心将进行 定期对研究中的所有动物进行临床评估， 保持和更新所有健康记录。 临床结局变量 提供给科学核心将包括动脉等措施， 血压、血流量和血清胆固醇。 核心还将包括 动物记录审查委员会将审查和保存所有 动物健康记录并查看所有尸检文件

The Animal and Clinical Core will be responsible for performing all surgical procedures and post-operative care for all animals in the study, and for the preparation, administration and monitoring of diets for the monkeys maintained on a high cholesterol regimen. The core will conduct clinical assessment of all animals in the study at regular intervals and maintain and keep current all health records. Clinical outcome variables provided to the Scientific Core will include such measures as arterial pressures, blood flow, and serum cholesterol. The core will also include the Animal Records Review Committee that will examine and maintain all animal health records and review all post-mortem files.