HOST CELL CYCLE REGULATION IN TRICHINELLOSIS

这方面的研究主要集中在分子和细胞方面。 宿主/寄生虫相互作用的各个方面。近期目标是建立一个 可持续、高质量的研究计划，取得有意义的进展 向控制传染病迈进。长期目标是使 对宿主/寄生虫领域的重大科学贡献 互动，培训新的独立调查人员，并推动这一点 研究领域通过多学科合作，准备 专题评论，以及同行评论和期刊编辑委员会的服务。 旋毛虫感染诱导骨骼肌细胞进入 进入S期，然后悬浮在细胞周期的G2/M期 在整个感染过程中，可能会持续数年。这部小说 对骨骼肌细胞的影响与表观 肌肉细胞去分化。研究的目的是确定 导致这些寄主变化的寄生因素。本研究具有广阔的应用前景。 应用于传染病和基础细胞生物学。

This research focus is in molecular and cellular aspects of host/parasite interactions. Immediate goals are to establish a sustainable, high quality research program which makes meaningful progress toward control of infectious diseases. Long-term goals are to make significant scientific contributions to the area of host/parasite interactions, to train new independent investigators, and to advance this research area through multidisciplinary collaborations, preparation of topical reviews, and service on peer review and journal editorial boards. Infection by Trichinella spirallis induces skeletal muscle cells to enter into S phase, which then become suspended in G2/M of the cell cycle throughout the course of infection, which can last for years. This novel effect on skeletal muscle cells is associated with the apparent dedifferentiation of muscle cells. Research is aimed at identifying parasite factors that induce these host changes. The research has broad application to infectious diseases and basic cell biology.