DRUG ABUSE AND PSYCHIATRIC COMORBIDITY

国家发改委的研究计划分为两部分：1.评估研究。我们计划 360例慢性精神病人药物滥用情况及模式研究 通过使用综合药物滥用评估对患病(CMI)个人进行评估 电池。已有180名CMI学员参加了为期7年的培训 收集了大量数据的精神病学研究，但不是关于药物的研究 虐待。其他180名CMI正在寻求药物滥用治疗。这 研究将描述药物滥用和社会人口统计学之间的联系， 精神病理学、家族史和临床病程。2.治疗 学习。我们计划评估创新治疗方法的疗效 精神分裂症可卡因滥用者，包括双盲 辅助性地昔帕明与安慰剂的药物治疗对比试验 综合治疗计划的背景。

The SDAC research plan has two parts: 1. Assessment Study. We plan to study the prevalence and patterns of drug abuse in 360 chronic mentally ill (CMI) individuals by using a comprehensive drug abuse assessment battery. 180 of the CMI are already enrolled in a 7 year prospective psychiatric study which has collected a wealth of data, but not on drug abuse. The other 180 CMI are seeking substance abuse treatment. This study will describe the association of drug abuse and sociodemographics, psychopathology, family history, and clinical course. 2. Treatment Study. We plan to assess the efficacy of innovative treatment approaches for schizophrenic cocaine abusers, including a double blind pharmacotherapy trial comparing adjunctive desipramine versus placebo in the context of a comprehensive treatment program.