Tissue Repair and Regeneration GRC

描述（由申请人提供）：2009年组织修复和再生戈登研究会议（GRC）将于2009年6月14日至19日在新罕布什尔州新伦敦的科尔比索耶学院举行。自1993年以来，组织修复和再生领域的九次成功的戈登会议每两年举行一次。该会议讨论了伤口愈合不充分和不适当的关键公共卫生问题，据估计，这一问题每年影响美国超过200万人。会议还关注组织再生，这是一个新兴领域，具有巨大的潜力，以改善因创伤或疾病而遭受严重组织损伤的患者的结果。该计划强调了不同组织之间修复过程的共性，并考虑了疾病对愈合的影响。该计划强调新兴的治疗和生物工程方法，可能会改善修复和促进再生。会议将强调修复和再生的分子和细胞机制的新概念，并将探讨伤口修复，组织再生和发育之间的联系。计划举办九次会议，包括1）系统生物学方法，2）愈合反应的应激源，3）再生，4）炎症，5）上皮细胞和增殖，6）干细胞，7）生物工程和治疗，8）纤维化和疤痕形成，以及9）修复/再生的遗传调控。演讲者和主题的组合已经被选中，以激发组织修复和再生领域的想法和合作。会议发言人将强调与修复和再生直接相关的未发表的新成果，并代表广泛的学科。每次会议将由一名在修复和再生机制方面工作出色的讨论调查员主持。为了向年轻的调查人员提供一个论坛，在一个有利的环境中介绍和讨论他们的调查结果，将从提交的摘要中再选出12名发言者;还将举行四次海报会议。将鼓励青年科学家和代表性不足的少数群体参与，并将提供奖学金支持他们的参与。在整个会议期间，将在正式和非正式场合促进高级和年轻调查员之间的互动，包括在用餐时间举行圆桌会议。对该计划的支持将确保会议将包括顶级科学家，并将为希望参加会议的杰出青年科学家提供急需的赞助。总的来说，这种支持将大大提高方案的质量和会议提供的教育机会。 公共卫生相关性：这次会议解决了组织修复不足和组织再生不足的关键公共卫生问题。不能完全重建组织是一个普遍存在的问题，在急性和慢性伤口以及恶性肿瘤和感染后都可以看到。本次会议与旨在改善愈合和组织再生的治疗方法的发展有关，这是一个新兴领域，具有巨大的潜力来改善数百万因创伤或疾病而遭受严重组织损伤的患者的结果。

DESCRIPTION (provided by applicant): The 2009 Gordon Research Conference (GRC) on Tissue Repair and Regeneration will be held from June 14-19, 2009 at Colby Sawyer College, New London, New Hampshire. The conference follows nine successful Gordon Conferences in the field of tissue repair and regeneration which have been held biennially since 1993. The conference addresses the critical public health problem of inadequate and inappropriate wound healing, a problem which is estimated to affect more than 2 million persons in the US annually. The conference is also concerned with tissue regeneration, an emerging field that has enormous potential to improve outcomes for patients who suffer substantial tissue damage due to trauma or disease. The program highlights the commonality of repair processes among different tissues and also considers the influence of disease on healing. The program emphasizes emerging therapeutics and bioengineering approaches that might improve repair and facilitate regeneration. The conference will emphasize new concepts in the molecular and cellular mechanisms that underlie repair and regeneration, and will explore links between wound repair, tissue regeneration, and development. Nine sessions are planned which include 1) Systems Biology Approaches, 2) Stressors of the Healing Response, 3) Regeneration, 4) Inflammation, 5) Epithelium and Proliferation, 6) Stem Cells, 7) Bioengineering and Therapeutics, 8) Fibrosis and Scar Formation, and 9) Genetic Regulation of Repair/Regeneration. The combination of speakers and topics has been selected to stimulate ideas and collaborations in the field of tissue repair and regeneration. The session speakers will emphasize novel unpublished results directly related to repair and regeneration and represent a wide range of disciplines. Each session will be chaired by a discussant investigator renowned for excellent work on the mechanisms of repair and regeneration. To provide young investigators with a forum in which to present and discuss their findings in a supportive environment, up to 12 additional speakers will be selected from submitted abstracts; four poster sessions will also be held. Participation by young scientists and underrepresented minorities will be encouraged, and scholarships to support their involvement will be offered. Throughout the conference, interaction among senior and young investigators will be promoted in both formal and informal settings, including hosted round tables at meal times. Support of this program will assure that the meeting will include top-level scientists, and will provide much needed sponsorship for outstanding young scientists who wish to attend the meeting. Overall, such support will greatly enhance the quality of the program and the educational opportunities provided by the meeting. PUBLIC HEALTH RELEVANCE: This conference addresses the critical public health problem of inadequate tissue repair and insufficient tissue regeneration. The inability to fully reconstitute tissue is a widespread problem that is seen in both acute and chronic wounds as well as following malignancy and infection. This conference is relevant to the development of therapeutics aimed at improved healing and tissue regeneration, an emerging field that has enormous potential to improve outcomes for the millions of patients who suffer substantial tissue damage due to trauma or disease.