INA-12

描述（由申请人提供） 该提案要求对2009年6月7日至12日在以色列耶路撒冷郊区的Ma'ale Hachamisha Kibbutz酒店和会议中心举行的国际神经毒理学协会（INA）-12会议提供部分支持。会议的广泛和长期目标是增加我们对神经毒理学的基本和应用方面的理解，重点是神经毒理学中的基因-环境相互作用。本次会议的具体目标是：1）邀请来自地球仪的35-40位代表神经毒理学和神经科学研究的关键和不同领域的杰出演讲者，2）让这些科学家在为期五天的会议期间与200名与会者在相对孤立的环境中讨论他们的研究结果。 该计划将于周日晚上开始，由希伯来大学和以色列耶路撒冷科学学院院长Hermona Soreq博士发表主题演讲。Soreq博士的飞机演讲的标题是“神经毒理学的分子生物学方法”。这八次会议将广泛讨论该领域的当前问题。周一的两场会议将集中在1）非哺乳动物的基因-环境相互作用和神经退行性变，2）发育中的神经系统的基因-化学相互作用：增殖，神经发生和分化。周二的两场会议将介绍：1）神经毒性表达中的新信号传导进展，2）体外和发育神经毒性测试策略。 星期四的两次会议将讨论：1）环境污染物和神经内分泌系统，2）和平利用分散的神经毒物。 周五上午的最后一次会议将集中在帕金森病的基因-环境相互作用。 此外，由参加神经毒理学研究生课程的学生组织和介绍的两个研讨会将完成口头报告（6月9日星期二下午和6月11日星期四上午）。 两个晚上的海报会议（星期一，6月8日和星期四，6月11日）将允许所有参与者在神经毒理学的这些和其他主题作出贡献。该应用程序的意义在于INA会议系列已成为推动研究人员和教育工作者参与神经毒理学各个方面的国际社会研究的主要场所，促进进入该领域的科学家的职业发展，并促进国际范围内的合作研究活动。本申请的健康相关性在于，由神经毒理学领域的主要权威人士的演讲所激发的讨论将定义影响人类神经健康领域需要实验解决的主要问题。因此，会议很可能会塑造未来的研究领域的发展暴露于退化与老化的神经系统，以及环境和遗传之间的相互作用，在沉淀神经变性，后者被选为本次会议的主题（INA-12）。

DESCRIPTION (provided by applicant) This proposal requests partial support for the International Neurotoxicology Association (INA)-12 Meeting, June 7-12, 2009, at Ma'ale Hachamisha Kibbutz Hotel and Convention Center in the outskirts of Jerusalem, Israel. The broad and long-term goal of the Conference is to increase our understanding of fundamental and applied aspects of neurotoxicology, with a strong emphasis on Gene-Environment Interactions in Neurotoxicology. The specific aims of this meeting are: 1) to invite 35-40 outstanding speakers from around the globe that represent the critical and diverse areas of neurotoxicological and neuroscience research, and 2) have these scientists present and discuss their findings with 200 participants during a five day Conference in a relatively isolated setting. The program will commence Sunday evening with a keynote lecture by Dr. Hermona Soreq, Dean, Faculty of Science, Hebrew University, and Jerusalem, Israel. The title of Dr. Soreq's planery lecture is "Molecular Biology Approach to Neurotoxicology". The eight sessions will broadly address current issues in the field. The two sessions on Monday will focus on 1) Gene-Environment Interactions and Neurodegeneration in Non-Mammals, and 2) Gene-Chemical Interactions in the Developing Nervous System: Proliferation, Neurogenesis and Differentiation. The two sessions on Tuesday will present: 1) Advances in Novel Signaling in the Expression of Neurotoxicity, and 2) Strategies for In Vitro and Developmental Neurotoxicity Testing. The two sessions on Thursday will address: 1) Environmental Contaminants and the Neuroendocrine System, and 2) Peaceful Use of Disastrous Neurotoxicants. The final session on Friday morning will focus on Gene-Environment Interactions in Parkinson's Disease. In addition, two Symposiums organized and presented by students participating in graduate programs in neurotoxicology will round out the oral presentations (Tuesday PM, June 9 and Thursday AM, June 11). Two evening poster sessions (Monday, June 8 and Thursday, June 11) will permit all participants to contribute to these and other topics in neurotoxicology. The significance of this application is that the INA Conference series has become a major venue that propels research in the international community of researchers and educators involved in all aspects of neurotoxicology, foster career development of scientists entering the field, and promote collaborative research activity with an international scope. The health relatedness of this application is that the discussions stimulated by the presentations of leading authorities in the field of neurotoxicology will define the major questions that require experimental resolution in areas that affect human neurological heath. Thus, the Conference is likely to shape future research in areas of developmental exposures to degeneration associated with the aging nervous system, as well as the interaction between the environment and genetics in precipitating neurodegeneration, the latter being chosen as the main theme of this meeting (INA-12).