The Visual Time Analog Scale for Enhanced Measurement of Acute and Chronic Pain

描述（由申请人提供）：本申请的目的是通过开发一种新型评估方法并证明其在急性和慢性疼痛患者中的可行性，改善疼痛强度和功能方面的测量。新方法要求患者使用高度直观的界面[视觉时间模拟（VITA）]来划分在相互排斥的、临床有效的疼痛状态中花费的时间。患者提供的分区生成有序的分类响应状态，这些状态具有非常理想的心理测量和统计特性，并且适合于个体临床监测和试验终点。该器械将通过允许患者沿非规则标尺沿着来回移动滑块来推广视觉模拟标尺界面。在试点测试中优化响应格式和类别后，我们将通过对200名急诊科急性疼痛患者和30名来自三级疼痛管理中心的慢性非癌症背痛患者进行评估来证明可行性。为了证明对变化的敏感性，我们将收集两种情况下的重复评估。我们将通过证明新方法在客观测量标准方面优于VAS标准来建立概念验证。患者将欣赏界面的简单和优雅。临床医生将重视对个体差异的更好描述、他们如何随着时间的推移而变化，以及通过这些更敏感的指标预测重要临床事件的能力的提高。统计学家将欣赏有序响应类别的原则性建模以及新量表允许的定性和连续分析选项的范围。 公共卫生相关性：该应用程序的目的是开发一种新的疼痛测量方法，将一天分为处于最小或剧烈疼痛状态的时间长度。新方法让患者使用简单的滑块来指示反应，但导致有效，可靠和复杂的评分和测量。

DESCRIPTION (provided by applicant): The objective of this application is to improve measurement of the intensity and functional aspects of pain by developing a novel assessment method and demonstrating its feasibility in both acute and chronic pain patients. The new approach asks the patient to use a highly intuitive interface [the Visual Time Analog (VITA)] to partition the time spent in mutually exclusive, clinically valid pain states. The partitions provided by the patients generate ordered categorical response states that have very desirable psychometric and statistical properties, and which will be suitable for individual clinical monitoring as well as trial endpoints. The devices will generalize the Visual Analog Scale interface by allowing patients to move sliders back and forth along an unruled scale. After optimizing response formats and categories in pilot testing, we will demonstrate feasibility by conducting evaluations of 200 Emergency Department patients with acute pain and 30 patients from a tertiary pain management center with chronic noncancer back pain. To demonstrate sensitivity to change, we will collect repeated assessments in both settings. We will establish proof of concept by demonstrating that the novel approach outperforms the VAS standard on objective measurement criteria. Patients will appreciate the simplicity and elegance of the interface. Clinicians will value the improved portrayal of how individuals differ, how they change over time, and the increased ability to predict important clinical events from these more sensitive measures. Statisticians will appreciate the principled modeling of ordered response categories and the range of qualitative and continuous analytic options the new scales permit. PUBLIC HEALTH RELEVANCE: The objective of this application is to develop a new method of pain measurement that divides the day into the lengths of time spent in minimal or intense pain states. The new method lets the patient use simple sliders to indicate response, but leads to scoring and measurement that is valid, reliable, and sophisticated.