MECHANICAL SYSTEMS RENOVATION

描述（由申请人提供）：比较医学部（DCM）是乔治敦大学唯一的集中动物资源核心设施。该机构的使命是为涉及实验动物的研究提供最佳的畜牧和兽医护理、专业技术支持和适当的监管监督。50，740平方米foot facility积极支持133名研究人员，提供218份动物护理和使用协议。该建筑由两个翼楼组成-“灰色”侧和“蓝色”侧，分别于1986年和1995年建造。57名研究人员在灰色地带饲养动物，并利用研究支持空间。 2006年，该大学启动了一个3阶段，5年计划，以取代23岁的机械系统的灰色一面。两个NCRR G20赠款项目目前正在进行中，以完成前两个计划阶段，包括更换非运行的加湿器;老化的排气扇，笼子清洗设备和建筑物管理系统;以及升级专用笼子清洗设施HV系统。 本提案旨在通过更换3台空气处理机组（阿胡斯）和相关机械支持设备，完成机构长期计划的第3阶段。要求更换“实物”设备，所有工作仅在机械空间（4 072平方英尺）内进行。对现有阿胡斯的重新设计将允许分阶段更换，同时尽量减少对通风和正在进行的研究的干扰。该项目采用符合LEED标准的可持续设计原则。在21个月的项目期间，美国的工作岗位（15-23个全职工作岗位）将保持不变。翻新后，将保留另外10个全职DCM职位。 资源核心设施灰色侧的机械系统改造对维持乔治敦大学的动物研究计划至关重要。设备/设施的最佳通风和适当卫生可保障动物健康，并支持PHS和其他校外支持研究的开展。如果这些机械系统失败，该机构可能会失去不可替代的动物模型，57个资助的研究项目，AAALACI认证和USDA注册。

DESCRIPTION (provided by applicant): The Division of Comparative Medicine (DCM) is the sole centralized animal resource core facility at Georgetown University. The mission of the facility is to provide optimal husbandry and veterinary care, specialized technical support and appropriate regulatory oversight for research studies involving laboratory animals. The 50,740 sq. foot facility actively supports 133 research investigators with 218 animal care and use protocols. The building is comprised of 2 wings - the "Grey" Side and the "Blue" Side, constructed in 1986 and 1995, respectively. Fifty-seven investigators house animals on the Grey Side and utilize research support spaces. In 2006, the University initiated a 3-phase, 5 year plan to replace the 23 year old mechanical systems on the Grey Side. Two NCRR G20 grant projects are currently underway to complete the first 2 planned phases including the replacement of non-operational humidifiers; aged exhaust fans, cage wash equipment and the building management system; and upgrade of the dedicated cage wash facility HV system. This proposal seeks to complete Phase 3 of the institutional long range plan by replacement of 3 air handling units (AHUs) and associated mechanical support equipment. "In-kind" equipment replacement is requested, with all work performed solely in mechanical spaces (4,072 sf). Redundancy of the existing AHUs will allow phased replacement with minimal disruption of ventilation and ongoing research studies. This project embraces sustainable design principles consistent with LEED criteria. American jobs (15-23 FTE) would be maintained during the 21 month project period. Ten additional full time DCM jobs would be maintained after renovation. Mechanical systems renovation on the Grey Side of the resource core facility is critical to maintain the animal research program at Georgetown University. Optimal ventilation and proper sanitation of equipment/facilities safeguard animal health and support the conduct of PHS and other extramural supported research. If these mechanical systems fail, the institution risks the loss of irreplaceable animal models, 57 funded research programs, AAALACi accreditation and USDA registration.