Administrative Core

项目总结--行政核心 奥布莱恩西北大学国家资源计划的行政核心使命 将作为第一个物理科学的中心-肾脏资源中心有两个：第一，创建 指导中心与中心一致所需的基础设施、流程和程序 第二，将该中心与更广泛的NIDDK国家资源网络连接起来。少校 该中心管理核心的目标是：(1)支持肾脏的跨学科物理科学 研究、培训和外联；(2)促进中心的协同作用和整合；(3)支持规划和 评估活动；以及(4)扩大研究人员在肾脏研究中的参与度和多样性。《中心》 对行政、生物医学和资源开发采用了多PI/PD领导模式 核心，由物理学家和肾脏研究人员组成的领导团队提供自上而下的 将物理科学方法与肾脏研究相结合。拟议的管理团队将由戴维斯博士。 Quaggin(首席调查员/主任)、Alfred George(联席-PI/PD/联席主任)和Sheila裁判(协理 董事)在制定有效的管理和培训活动战略方面具有丰富的经验。 西北大学国家资源中心行政核心将履行其 使命“通过应用物理科学实现变革性的肾脏研究”，具体如下 六个具体目标：1.领导、管理和整合NU-NRC的所有方面，并确保中心的资源 在全国范围内共享。2.与国家协调中心和其他国家协调中心合作：(A) 优先处理外部请求，以最大限度地利用网络资源；(B)加强在全国的宣传和影响； 以及(C)教育社区有关肾脏研究的知识。3.监测新兴的科学技术、方法、 模型和概念，并促进其应用，以满足国家肾脏研究界的需要。4. 为扩大肾脏研究人员队伍作出贡献。5.增强中心和肾脏的多样性 在西北大学做研究。6.制定和实施暑期学生充实计划。 NU-NRC提供了强大的基础设施，用于提供已建立的基于纳米技术的翻译 通过其生物医学资源核心和强有力的监督向肾脏研究人员提供药物的能力 通过发展以物理科学为基础的技术促进其新应用的机制 资源核心。此外，该中心还将利用一项完善的SciHigh计划，即广泛的培训 机会，以及试点资金，以扩大和多样化有才华的肾脏研究人员队伍，并降低 早期研究人员的研究障碍。一套定义明确的中心指标、里程碑和时间表 将有助于正在进行的对NU-NRC进展的评估。最后，NU-NRC领导层准备支持 O‘Brien Kidney财团，并最大化整个财团资源中心的价值。

PROJECT SUMMARY – ADMINISTRATIVE CORE The mission of the Administrative Core of the proposed O'Brien Northwestern University National Resource Center that will serve as the first Physical Sciences-Kidney Resource Center is two-fold: first, to create the infrastructure, processes and procedures that are required to guide the Center in accord with the Center framework; and second, to connect the Center with the broader NIDDK National Resource Network. The major goals of the Center's Administrative Core are to (1) Support transdisciplinary physical sciences in kidney research, training, and outreach; (2) Foster synergy and integration of the Center; (3) Support planning and evaluation activities; and (4) Expand participation and diversity of investigators in kidney research. The Center has adopted a multi-PI/PD leadership model for the Administrative, Biomedical, and Resource Development Cores, with leadership teams consisting of physical scientists and kidney researchers to provide top-down integration of physical sciences approaches and kidney research. The proposed administrative team of Drs. Quaggin (Principal Investigator/Director), Alfred George (Co-PI/PD/Co-Director), and Sheila Judge (Associate Director) brings extensive experience in developing effective strategies for management and training activities. The Administrative Core of the Northwestern University National Resource Center (NU-NRC) will fulfill its mission “to enable transformative kidney research through the application of physical sciences” with the following six Specific Aims: 1. Lead, manage, and integrate all aspects of the NU-NRC and ensure that Center resources are shared nationally. 2. Collaborate with the National Coordinating Center (NCC) and other NRCs to: (a) Prioritize external requests to maximize access to network resources; (b) Enhance national outreach and impact; and (c) Educate the community about kidney research. 3. Monitor emerging scientific technologies, methods, models, and concepts and facilitate their application to the needs of the national kidney research community. 4. Contribute to the expansion of the pool of kidney investigators. 5. Enhance the diversity of the Center and kidney research at Northwestern. 6. Develop and implement a Summer Student Enrichment program. The NU-NRC offers a robust infrastructure for providing established nanotechnology-based translational capabilities for drug delivery to kidney researchers through its Biomedical Resource Core and strong oversight mechanisms to foster new applications of physical science-based technologies through its Developmental Resource Core. In addition, the Center will leverage a well-established SciHigh program, a wide array of training opportunities, and pilot funding to expand and diversify the pool of talented kidney researchers and lower the barriers to research for early stage investigators. A well-defined set of Center metrics, milestones and timeline will aid ongoing evaluation of NU-NRC progress. Finally, NU-NRC leadership are poised to support the work of the O'Brien Kidney Consortium and maximize the value of resource centers across the consortium.