Don S. Fredrickson Lipid Research Conference

摘要 唐·S·弗雷德里克森脂质研究会议(FLRC)汇集了科学家和 受训者研究脂和脂蛋白代谢对发育和 心脏代谢疾病的治疗。FLRC是以已故的唐·S·弗雷德里克斯的名字命名的 在1966-1974年间担任国家心脏研究所(现在的NHLBI)主任，后来 NIH，开发了血脂异常(I-V型)的临床分类，描述了Tangier的 疾病，并在脂蛋白代谢方面取得了开创性的发现。最重要的是，他训练 基础和临床科学家和实践者，他们对 脂蛋白代谢领域。 自2016年以来，对外关系与合作委员会采用了轮流主办的机构模式，并由 肯塔基大学(‘16，`17，’21)，范德比尔特大学(‘18，`23)， 辛辛那提(‘19)、杜克大学和北卡罗来纳大学(’22)。 2024年由威斯康星医学院主办，2025年返回英国。 2023年弗雷德里克森会议的主旨演讲包括哈佛大学的芭芭拉·卡恩 还有艾伦·雷梅利，来自国家心肺血液研究所。专题科学会议 内容包括：肠道微生物组对脂类代谢的调控、脂类中稳定同位素的研究 代谢、动脉粥样硬化消退和效应细胞增多症、甘油三酯调节剂 代谢与脂蛋白脂肪酶。对外汉语教学与研究中心非常重视学生和研究员， 早期职业教员，以及代表性不足的群体。根据这一使命，议程 还包括专门为受训者举办的额外科学会议、“海报推介”会议(5-7个， 90秒的演讲)，以及评判海报环节。经过精心设计，议程为每一个人提供了 参加培训的学员有机会在舞台上展示他们的研究成果，并与 这一领域，并拓宽了他们的范围和对脂代谢和 心脏代谢性疾病。 我们的形式鼓励各级科学家之间的非正式互动，提供 创新的思想交流和合成方法将推动脂质领域的发展 研究进展。这次会议将产生很大的影响，因为该计划涉及基础科学 这一发现具有临床意义。因此，预计这次会议将提供新的 不仅对脂类代谢的基本方面，而且对如何治疗，并最终 治愈，各种各样的心脏代谢性疾病状态。

ABSTRACT The Don S. Fredrickson Lipid Research Conference (FLRC) brings together scientists and trainees investigating the impact of lipid and lipoprotein metabolism on the development and treatment of Cardiometabolic Disease. The FLRC is named after the late Don S. Fredricks who as the director of the National Heart Institute (now the NHLBI) from 1966 – 1974 and later the NIH, developed the clinical classification for dyslipidemias (Type I-V), described Tangier's Disease, and made seminal discoveries in lipoprotein metabolism. Most importantly, he trained both basic and clinical scientists and practitioners who have had a tremendous impact on the field of lipoprotein metabolism. Since 2016 the FLRC has employed a rotating institutional host model and has been hosted by the University of Kentucky ('16, `17, '21), Vanderbilt University ('18, `23), the University of Cincinnati ('19), Duke University and the University of North Carolina ('22). The FLRC will be hosted by the Medical College of Wisconsin in 2024 and return to UK in 2025. Keynote Lectures at the 2023 Fredrickson conference include Barbara Kahn, Harvard University and Alan Remaley, National Heart Lung and Blood Institute. The thematic scientific sessions include: Intestinal Microbiome Control of Lipid Metabolism, Stable Isotope Studies in Lipid Metabolism, Atherosclerosis Regression and Efferocytosis, Modulators of Triglyceride Metabolism & Lipoprotein Lipase. The FLRC places a strong emphasis students and fellows, early career faculty, and underrepresented groups. In accordance with that mission, the agenda also includes additional scientific sessions dedicated for trainees, a “Poster Pitch” session (5-7, 90-second presentations), and a judged poster session. By design, the agenda affords every trainee in attendance the opportunity to present their research on stage, network with leaders in the field, and broaden their scope and understanding of research in lipid metabolism and Cardiometabolic Diseases. Our format encourages informal interactions between scientists at all levels, providing an innovative approach to the exchange of ideas and synthesis that will move the field of lipid research forward. The conference will have high impact as the program spans basic science discovery to clinical significance. It is therefore expected that the meeting will provide new insights not only into basic aspects of lipid metabolism, but also how to treat, and ultimately cure, a wide variety of Cardiometabolic Disease states.