Cardiovasology

描述（由申请人提供）：修订后的申请是“心血管学”培训计划31-35年的继续资助申请。该计划成功地完成了其使命，为心血管医学和生物学的独立研究事业做好准备的医生和非医生科学家。学员在发表高质量的同行评审论文方面表现出色，并在申请资助和学术安排方面建立了良好的记录。在每一个获奖年份，所有的名额都被有才华的医学博士和博士候选人填满了。梅奥诊所为以人类疾病为中心主题的基础、临床和人口心血管科学培训提供了良好的环境。成就包括强大的学员招聘和保留，与优秀教师的互动指导，健全的组织结构和有利的环境，产生富有成效的学术生涯。建立在卓越的传统，更新开发，以满足最高的教育标准，并提供尖端的博士后培训。课程是根据每个学员的背景和职业道路定制的。心衰、缺血性心脏病和心律失常等疾病主题是培训的重点，反映了全国发病率和死亡率的趋势。致力于NHLBI计划重点，修订后的应用程序整合了最先进技术的多学科培训，综合课程，以实现从实验室到床边的科学需求不断发展的领域的能力，以及研究生存技能的教学和实践指导。该项目汇集了一个由基础科学家、临床研究人员和人口科学家组成的合作团队，他们的专业知识互补。为了响应NIH研究部的建议，重新提交的报告包含了一项新的研究员到教师的职业发展计划，旨在促进受训者早日过渡到独立的教师地位，并实施了一项加强的少数民族招聘计划，以增加接受培训的少数民族个人的数量。该项目利用了技术平台，以及梅奥诊所授予硕士/博士学位的学位授予项目。获得基因组学、蛋白质组学、代谢组学和生物信息学方面的技能，并将其应用于心脏病的研究，对于培养学员为未来的生物医学做好准备至关重要。新的产品包括遗传流行病学和医学信息学；药物基因组学;计算生物学;纳米;还有细胞疗法。修订后的申请强调了“心血管学”培训计划的愿景，即提供最先进的培训，吸引和指导内科科学家和基础研究人员，他们将成为心血管研究生物学和医学的领导先锋。

Description (provided by applicant): The revised application is a request for continuation of funding for years 31-35 of the "Cardiovasology" Training Program. This Program has successfully accomplished its mission in preparing physicians and nonphysician scientists for independent research careers in cardiovascular medicine and biology. Trainees have excelled in publishing high quality peer-reviewed papers, and have established a track-record of grant applications and academic placement. All slots were filled, in each of the awarded years, by talented MD and PhD candidates. Mayo Clinic has provided an outstanding environment for training in basic, clinical and population cardiovascular sciences with human disease as the central theme. Accomplishments include strong trainee recruitment and retention, interactive mentoring with outstanding faculty, robust organizational structure, and conducive environment, yielding productive academic careers. Building on a tradition of excellence, the renewal is developed to meet the highest educational standards, and offer cutting-edge postdoctoral training. The curriculum is customized to match the background and career path of each trainee. The disease theme of heart failure, ischemic heart disease and heart rhythm disorders is the focus of training, reflecting national morbidity and mortality trends. Committed to NHLBI programmatic emphases, the revised application integrates multidisciplinary training in state-of-the-art technologies, a comprehensive curriculum to achieve competencies in evolving areas of scientific need from the bench to the bedside, and didactic and practical instruction in research survival skills. The Program brings together a collaborative team of basic scientists, clinical investigators and population scientists with complementary expertise. In response to NIH Study Section recommendations, the resubmission incorporates a new fellow-to-faculty career development program established to foster an earlier transition of trainees into independent faculty status, and an enhanced minority recruitment plan implemented to increase the number of minority individuals who receive training. The Program capitalizes on enabling technological platforms, and degree-granting programs at the Mayo Clinic that lead to master/doctorate degrees. Acquisition of skills in genomics, proteomics, metabolomics and bioinformatics, applied to the study of heart disease, is paramount to preparing trainees for the biomedicine of tomorrow. New offerings include genetic epidemiology and medical informatics; pharmacogenomics; computational biology; nanomedicine; and cell-based therapies. The revised application underscores the vision of the "Cardiovasology" Training Program to provide most advanced training, attracting and mentoring physician-scientists and fundamental investigators who will comprise the vanguard of leadership in the biology and medicine of cardiovascular research.