Administrative Core Fragile X

委员会的组织结构图见上文第二.A.2节（图二.A.1）。它 概述了主任、协理主任和 行政核心的研究核心和个人的研究项目。缘于这里有 对于已批准在MRDRC中访问核心的研究项目，我们已通过以下方式代表它们： 主题，括号中的数字表示单个项目的数量 在每一个主题中得到支持。上文表二.A.2分别列出了这些项目。 博士根据内部咨询委员会的建议，Huda Zoghbi被任命为主任 在爱德华·麦凯布博士离开加州大学洛杉矶分校担任儿科主任之后。Zoghbi博士一直担任 该委员会已在该委员会工作了八年多，并将继续担任这一职务。她是一个董事会认证 儿科神经科医师，具有丰富的研究成果。她带来的兴趣和经验与许多人类遗传疾病与精神发育迟滞作为一个组成部分。她对Rett综合征特别感兴趣。Zoghbi博士是儿科、神经病学、神经科学和分子与人类遗传学教授，也是霍华德休斯医学研究所的研究员。 博士大卫纳尔逊在目前的资金期间担任该委员会的副主任 在这一过程中，我们将继续发挥这一作用。纳尔逊博士是一个人类分子 遗传学家谁带来了丰富的经验和兴趣，在精神发育迟滞的MRDDRC 通过他在脆性X综合征、FRAXE综合征和失禁方面的活动， 色素基因及其产物。他也有管理大型中心的经验， 美国国立卫生研究院资助的人类基因组中心的副主任和主任。纳尔逊医生将 如果主任丧失履行职责的能力，他将继续 建议和协助主任在运作的MRDDRC沿着行政和 科学咨询委员会。

The organizational chart of the BCM MRDDRC is shown under section II.A.2 above (Figure II.A.1). It outlines the administrative responsibilities of the Director, the Associate Director and the Administrative Core to the Research Cores and individual research projects. Due to the number of research projects approved for access to cores in the BCM MRDDRC, we have represented them by their thematic topics, with a number in parentheses indicating the number of individual projects supported within each theme. Table II.A.2, above, lists the projects individually. Dr. Huda Zoghbi was appointed Director upon recommendation of the internal advisory committee after Dr. Edward McCabe left BCM to chair Pediatrics at UCLA. Dr. Zoghbi has been Director of the BCM MRDDRC for over eight years and will continue in that capacity. She is a board certified pediatric neurologist with abundant research accomplishments. She brings interest in and experience with numerous human genetic disorders with mental retardation as a component. She has a particular interest in Rett syndrome. Dr. Zoghbi is Professor of Pediatrics, Neurology, Neurosciences and Molecular and Human Genetics and an investigator of the Howard Hughes Medical Institute. Dr. David Nelson has served as Associate Director of the BCM MRDDRC during the current funding cycle, and will continue in that role in this proposed renewal. Dr. Nelson is a human molecular geneticist who brings extensive experience and interest in mental retardation to the MRDDRC through his activities in characterizing the fragile X syndrome, FRAXE syndrome and incontinentia pigmenti genes and their products. He also has prior experience in managing large Centers both Associate Director and Director of the NIH-funded BCM Human Genome Center. Dr. Nelson will be responsible for the BCM MRDDRC should the Director become incapacitated and he will continue to advise and assist the Director in the operation of the MRDDRC along with the Administrative and Scientific Advisory Committee.