Sickle cell scholar component

本提案描述了拟议的Sickle Cell学者的职业发展计划。下一个 镰状细胞病(SCD)的一代临床研究人员将需要包括具有以下技能的个人， 态度、早期研究培训和经验，以利用SCD快速发展的进展 研究。在制定这一计划时，我们将使用现有的研究基础设施，包括我们的研究生 约翰霍普金斯大学医学院临床研究培训计划(GTPCI) 约翰霍普金斯大学彭博公共卫生学院和一个有指导的研究项目提供 为镰刀细胞学者提供临床研究和方法学方面的强化培训。我们的具体目标是：a) 识别、培训和培养一名富有创造力和成功的临床研究人员，并有能力与之互动 参与并领导多学科团队参与临床研究，解决复杂问题 并成为全国SCD研究的领先者；b)为学员提供必要的技能、知识、 对SCD临床研究事业成功的态度和经验。这项培训将包括 接触国家和国际领导人，并在必要的多个学科中开设课程 成功的临床研究，包括临床试验设计、流行病学、统计学、研究伦理和 保护人类主体，以及学者与他的合作开发的一个研究项目 Mentor；c)提供访问约翰霍普金斯大学学院丰富的指导环境的机会 医学院和公共卫生学院提供最佳接触的镰刀细胞学者进行研究 经验和培训。仔细和广泛的指导将是这一努力的基石， 接触和参与尖端研究。通过这个计划，我们最终的目标是开发 一位镰刀细胞学者，他将成为一名富有创造力的独立研究员，照顾SCD患者和 在以患者为中心的SCD研究中发挥领导作用。

This proposal describes the career development plan for the proposed Sickle Cell Scholar. The next generation of clinical researchers in sickle cell disease (SCD) will need to include individuals with the skills, attitudes, early research training and experience to capitalize on rapidly developing progress in SCD research. In developing this plan, we will use established research infrastructure, including our Graduate Training Program in Clinical Investigation (GTPCI) at the Johns Hopkins University School of Medicine and Johns Hopkins University Bloomberg School of Public Health and a mentored research project to provide intensive training in clinical research and methodology for the Sickle Cell Scholar. Our specific aims are: a) To identify, train and develop a creative and successful clinical investigator, with the capability to interact with, participate in, and lead multidisciplinary teams involved in clinical research, address complex problems and become a national leader in SCD research; b) To provide the trainee with the requisite skills, knowledge, attitude and experience for a successful career in clinical research in SCD. This training will include exposure to national and international leaders and curriculum in the multiple disciplines necessary for successful clinical research, including clinical trials design, epidemiology, statistics, research ethics and human subjects protection, as well as a research project developed by the Scholar in conjunction with his mentor; c) To provide access to the rich mentoring environment of the Johns Hopkins University School of Medicine and School of Public Health to provide optimal exposure of the Sickle Cell Scholar to research experiences and training. Careful and extensive mentoring will be the cornerstone of this effort, with exposure to and involvement in cutting edge research. Through this program, we ultimately aim to develop a Sickle Cell Scholar, who will become a creative, independent investigator, care for patients with SCD and assume a leadership role in SCD patient-oriented research.