Increasing Physical Activity Among Inactive Bariatric Surgery Patients

描述(由申请人提供)： 这项指导研究科学家发展奖(K01)的目标是让Dale Bond博士成为一名独立科学家，研究治疗严重肥胖症的创新行为方法，特别强调增加体力活动的策略。通过教学和直接指导的培训经验相结合，该培训计划将为他提供以下领域的知识和技能：严重肥胖症和减肥外科手术；严重肥胖症的行为治疗，重点是增加和测量体力活动的策略；以及严重肥胖症临床试验的方法、统计和伦理。在整个颁奖过程中，邦德博士将与他的导师雷纳·荣博士以及他的合作导师哈里·萨克斯博士(外科医生)、约翰·雅基奇奇博士(运动生理学家)和约瑟夫·法瓦博士(量化心理学家)密切合作。米里亚姆医院/布朗医学院的资源，再加上专家顾问团队的指导，将为邦德博士提供实现其长期职业目标的理想环境。严重肥胖或超重超过100磅的美国人的比例正在迅速增加。这是一个重大的公共卫生挑战，因为与肥胖程度较低的人相比，严重肥胖的人有更高的并存率，对卫生保健系统造成的损失也更大。对于这些人来说，减肥手术目前是产生实质性和长期减肥效果的首选治疗方法，尽管结果各不相同。缺乏体力活动是影响手术成功的一个行为因素。然而，为增加减肥手术患者的体力活动而进行的结构化行为干预尚未进行。因此，这项拟议的研究包括一项随机对照试验，比较增加体力活动的行为干预、减少久坐行为的行为干预和标准护理对照组对75名体力活动水平较低的成年减肥手术患者手术前和术后客观测量的体力活动变化的影响。这项研究的长期目标是通过创新的行为策略增加体力活动来改善减肥手术的结果。 公共卫生相关性：减肥手术是目前治疗严重肥胖者最有效的治疗方法，尽管结果各不相同。缺乏体力活动是影响手术成功的行为因素之一。因此，本研究项目的目标是通过创新性地针对体力活动或久坐行为来增加体力活动，并改善体力活动不足的患者的减肥手术结果。

DESCRIPTION (provided by applicant): The goal of this Mentored Research Scientist Development Award (K01) is to prepare Dr. Dale Bond to become an independent scientist studying innovative behavioral approaches for the treatment of severe obesity, with specific emphasis on strategies to increase physical activity. Through a combination of didactic and direct mentored training experiences, this training plan will provide him with knowledge and skills in the following areas: severe obesity and bariatric surgical procedures; behavioral treatment of severe obesity, with emphasis on strategies to increase and measure physical activity; and methodology, statistics and the ethics of clinical trials in severe obesity. Dr. Bond will work closely with his mentor, Dr. Rena Wing, and his multidisciplinary team of co-mentors Drs. Harry Sax (surgeon), John Jakicic (exercise physiologist) and Joseph Fava (quantitative psychologist) throughout the course of the award. The resources at The Miriam Hospital/Brown Medical School combined with the mentoring by an expert advisory team will provide Dr. Bond with the ideal environment to achieve his long-term career objectives. The proportion of Americans who are severly [sic] obese or more than 100 pounds overweight is rapidly increasing. This presents a significant public health challenge as severely obese individuals have a higher rate of comorbidities and exact a greater toll on the health care system than less obese persons. For these individuals, bariatric surgery is currently the treatment of choice for producing substantial and long-term weight loss, although outcomes vary. Low physical activity is one behavioral factor that undermines surgical success. However, structured behavioral interventions to increase physical activity in bariatric surgery patients have not been conducted. Thus, the proposed study involves a randomized controlled trial comparing the effects of a behavioral intervention to increase physical activity, a behavioral intervention to decrease sedentary behaviors, and a standard care control group on changes in objectively-measured preoperative and postoperative physical activity among 75 adult bariatric surgery patients with low level of physical activity. The long-term goal of this research is to improve bariatric surgery outcomes through innovative behavioral strategies to increase physical activity. PUBLIC HEALTH RELEVANCE: Bariatric surgery is currently the most effective treatment for severely obese individuals, although outcomes vary. Low physical activity is one behavioral factor that can undermine surgical success. Therefore, the goal of this research project is to increase physical activity and improve bariatric surgery outcomes in patients with low physical activity through innovatively targeting physical activity or sedentary behaviors.