Training Clinical Veterinarians in Nonhuman Primate Clinical Medicine

描述(由申请人提供)：NCRR认识到越来越缺乏受过训练并熟练掌握用于生物医学研究的圈养非人类灵长类动物的临床管理的兽医。我们在这里申请资金，支持三名DVM后住院医生进行为期两年的灵长类医学培训。维克森林大学医学院(WFUSM)和比较医学部在使用NHP人类疾病模型以及在实验动物和比较医学方面培训兽医方面已有50年的历史。这项培训的重点是发展管理、医学、病理学和在生物医学研究中使用NHP的专门知识。研究培训补助金实验室动物和比较医学培训(亚当斯先生，目前的PI)是由NCRR支持的T32赠款持续资助的第48个年头。此外，WFUSM目前支持DVM在实验动物医学和诊断病理学方面的住院医师培训。因此，这里提出的培训是对现有方案的补充，而不是取代。培训学院有16名成员，他们都有比较医学方面的任命，其中14人是DVM，4人是ACLAM文凭，2人是ACVP文凭。学员将选择一名DVM导师，该导师还可以担任有限范围临床研究项目的顾问，该项目将作为他们培训的一部分。所有学员都将有一名ACLAM文凭作为导师或共同导师。培训将包括医学灵长类动物学、生物医学研究中的动物模型以及灵长类动物行为和心理健康方面的课程。还包括灵长类临床医学和诊断病理学的轮换；基于经验的IACUC培训；以及非人类灵长类研究资源群体管理的短期课程：SPF和遗传考虑，动物设施成本核算，以及职业健康。受训人员还将参加每周的杂志俱乐部、临床大轮回和比较病理学会议。最后，西南生物医学研究基金会(Southwest Foundation For Biomedical Research)和巴斯特罗普的M.D.安德森癌症研究中心(M.D.安德森癌症研究中心)(获得黑猩猩和新热带灵长类动物的经验)的外部资助也包括在内。

DESCRIPTION (provided by applicant): The NCRR recognizes a growing shortage of veterinarians trained and proficient in the clinical management of captive nonhuman primates used in biomedical research. We request here funding to support three post-DVM residents for two years of training in primate medicine. The Wake Forest University School of Medicine (WFUSM) and the Section of Comparative Medicine have a 50-year history in the use of NHP models of human disease and in the training of veterinarians in laboratory animal and comparative medicine. This training has focused on development of expertise in the management, medicine, pathology and use of NHPs in biomedical research. The research training grant Laboratory Animal and Comparative Medicine Training (MR Adams, current PI) is in its 48th year of continuous funding by and NCRR-supported T32 grant. In addition, WFUSM currently supports residency training of DVMs in laboratory animal medicine and diagnostic pathology. Thus, the training proposed here complements, but does not replace, existing programs. There are 16 members of the training faculty, all have appointments in Comparative Medicine, 14 of these are DVMs, 4 are ACLAM diplomates and 2 are ACVP diplomates. Trainees will choose a DVM mentor, who may also serve as advisor on a limited-scope clinical research project to be conducted as part of their training. All trainees will have an ACLAM diplomate as a mentor or co-mentor. Training will include courses in Medical Primatology, Animal Models in Biomedical Research, and Primate Behavior and Psychological Wellbeing. Also included are rotations in primate clinical medicine and diagnostic pathology; experience-based IACUC training; and short courses in The Management of Nonhuman Primate Research Resource Colonies: SPF and Genetic Considerations, Cost Accounting for Animal Facilities, and Occupational Health. Trainees will also participate in weekly Journal Clubs, Clinical Grand Rounds and the Comparative Pathology Conference. Finally, externships to the Southwest Foundation for Biomedical Research (for experience with baboons and a short course in genetic management of nonhuman primate colonies) and M.D. Anderson Cancer Research Center at Bastrop (for experience with chimpanzees and neotropical primates) are also included.