South Africa Tuberculosis/AIDS Training

描述（由申请人提供）：南非是全球结核病负担最高、结核病/艾滋病毒负担最高和艾滋病毒负担最高的五个国家之一。在临床、操作和卫生服务研究方面缺乏经验丰富的调查人员是南非未能实现结核病控制目标的主要原因之一。这是一份来自三所南非大学（威特沃特斯兰德大学、开普敦大学、斯泰伦博斯大学）和两所美国大学（约翰霍普金斯大学和查佩尔山的北卡罗来纳州大学）的两份先前规划赠款的联合申请，旨在创建一个全面的结核病培训计划。我们将在南非教授艾滋病、结核病、研究方法和研究伦理方面的短期课程，为南非和美国的中长期培训物色有才华的南非人，在培训期间指导他们，在培训结束后资助他们进行初步研究，并帮助他们在南非建立独立的职业生涯。我们还与马拉维大学ICOHRTA建立了联系，以提供南南培训机会和其他三项Fogarty赠款：道格拉斯·瓦斯纳-在比勒陀利亚大学进行生物伦理学培训; Mike Merson和玛丽Crewe-在比勒陀利亚大学和耶鲁大学进行艾滋病毒预防培训; Slim Karim-在夸祖鲁-纳塔尔大学和哥伦比亚大学进行培训。具体目标：1.通过21个硕士/博士生年和28个中期经验培训一批高级教师，以开展与南非有关的结核病/艾滋病毒问题的业务、保健服务和临床研究。2.通过在赠款管理、良好临床实践、人类受试者保护、基础流行病学以及结核病和艾滋病方面的短期经验，培训一批初级教职员工、政府和非政府组织工作人员。学术界和非政府组织通过2004年公共卫生领导力计划中的领导力培训，以一种协调一致的方式开展工作。5.通过召开以结核病/艾滋病毒为重点的年度会议，加强南非各地的威特沃特斯兰德大学、开普敦大学、比勒陀利亚大学、斯泰伦博斯大学和夸祖鲁-纳塔尔大学的艾滋病毒/结核病调查人员之间的联系。

DESCRIPTION (provided by applicant): South Africa is one of the five countries worldwide that rank in the top ten of highest TB burden, highest TB/HIV burden and highest HIV burden. The lack of experienced investigators in clinical, operational and health services research s one of the main reasons behind the failure of South Africa to meet its tuberculosis control targets. This is a combined application from two prior planning grants from three South African universities (University of the Witwatersrand, University of Cape Town, Stellenbosch University) and two US universities (Johns Hopkins and University of North Carolina at Chapel Hill) to create a comprehensive TB training program. We shall teach short term courses in HIV, TB, research methods and research ethics in South Africa, identify talented South Africans for intermediate and long term training in South Africa and the US, mentor them throughout their training, fund them for preliminary research after completion of training and help them establish independent careers in South African. We have also established a link with the University of Malawi ICOHRTA to provide South to South training opportunities and the three other Fogarty grants: Douglas Wassnaar-bioethics training at University of Pretoria; Mike Merson and Mary Crewe-HIV prevention training at University of Pretoria and Yale; Slim Karim at University of KwaZulu-Natal and Columbia. Specific aims: 1 Train a cadre of senior faculty through 21 student years of MPH/PhD and 28 intermediate term experiences to carry out operations, health services and clinical research studying TB/HIV questions relevant to South Africa. 2.Train a cadre of junior faculty and staff, government and NGO staff through short term experiences in grants management, Good Clinical Practice, Human subjects protections, basic epidemiology and TB and HIV S.Train a team of at least 4 leaders from government, academia and NGOs to work in a cohesive manner through leadership training in the Public Health Leadership program at UNC 4.Create a sustainable TB training program in South Africa which does not require US investigator input 5.Strengthen the linkages of HIV/TB investigators throughout South Africa at University of the Witwatersrand, University of Cape Town, University of Pretoria, Stellenbosch University and University of KwaZulu-Natal through annual meetings focused on TB/HIV.