Administrative Core

行政核心负责协调P30 EHS核心中心的活动，包括整合所有中心组件、管理日常运营、计划评估以及各种文书和会计职能。分子毒理学中心最近扩展为一个更全面的组织，在一个共同的“保护伞”下管理几个单位，这是范德比尔特大学负责研究的副校长(现任医学院院长)J.Balser博士于2006年发布的新的五年战略计划的一部分。在历史上，该中心由两个主要计划组成：P30 EHS核心中心赠款(本申请，P30 ES000267)和附属的环境毒理学培训计划(T32 ES007028)。今天，P30 EHS核心中心和培训计划继续为该中心提供分子毒理学方面的大部分研究和培训基础设施，但现在该中心的行政保护伞下还包括其他几个计划和倡议： ？与Meharry医学院在环境健康方面的高级研究合作(S11 ES014156)锰健康研究方案(由国防部资助) ？以患者为导向的职业发展计划(K12 ES015855)，为环境健康科学学者提供支持(更详细地描述，第146-151页) ？新资助的NIEHS T35医科学生暑期短期研究及培训计划(T35 ES016534-01) ？与橡树岭国家实验室合作的NIEHS超级基金基础研究计划，重点关注汞中毒的易感性机制(提交04/08)。这一轮的优先分数在资金方面不具竞争力，计划在04/10年度重新提交。 ？关于药物诱导的细胞毒性机制的提议的机构赞助的计划 因此，行政核心在利用资源方面发挥了重要作用，目的是扩大范德比尔特在与人类健康有关的环境毒理学领域的存在。

The Administrative Core is responsible for coordinating P30 EHS Core Center activities, including the integration of all Center components, management of day-to-day operations, program assessment, and various clerical and accounting functions. The Center in Molecular Toxicology has recently expanded into a more comprehensive organization that administers several units under a common "umbrella," as part of the new 5-year strategic plan distributed in 2006 by Vanderbilt's Associate Vice-Chancellor for Research (and current Dean of the School of Medicine), Dr J. Balser. Historically, the Center consisted of two major programs: the P30 EHS Core Center grant (this application, P30 ES000267) and the affiliated training program in environmental toxicology (T32 ES007028). Today the P30 EHS Core Center and training programs continue to provide much of the research and training infrastructure for the Center in Molecular Toxicology, but several other programs and initiatives are now included under the Center's administrative umbrella: ¿ Advanced Research Cooperation in Environmental Health (ARCH) with Meharry Medical College (S11 ES014156) Manganese Health Research Program (funded by the Department of Defense) ¿ Patient-Oriented Career Development Program (K12 ES015855), which provides support for environmental health science scholars (described in further detail, pp. 146-151) ¿ A newly funded NIEHS T35 short-term summer research and training program for medical students (T35 ES016534-01) ¿ An NIEHS Superfund Basic Research Program with Oak Ridge National Laboratory focusing on mechanisms of susceptibility to mercury toxicity (submitted 04/08). The priority score from this round was not competitive for funding, and a resubmission is planned for 04/10. ¿ A proposed institutionally-sponsored program in mechanisms of drug-induced cellular toxicity Thus the Administrative Core has been instrumental in leveraging resources with the goal of amplifying Vanderbilt's presence in the field of environmental toxicology as it relates to human health.