NICHD Maternal Fetal Medicine Units Network

描述（由申请人提供）：伯明翰亚拉巴马大学（DAB）母胎医学部坚定地致力于继续高水平参与NICHD MFMU网络，以调查临床产科问题，特别是与低出生体重、早产和妊娠并发症有关的问题。我们在这些领域的临床试验方面拥有丰富的经验，以及强大、稳定和经过验证的研究基础设施。我们一直是MFMU网络过去三个五年周期的参与中心。在此期间，我们在指导和小组委员会层面为网络提供研究方向方面发挥了领导作用，为网络试验的进行做出了贡献，并介绍和出版了这些试验产生的数据。九个不同的当前UAB调查员已经或正在担任网络协议主席或小组委员会成员。三分之一的网络出版物是由UAB调查员首次撰写的，在2002-2005年国家会议上的95次网络介绍中，UAB调查员介绍了21次。在当前的5年周期中，根据患者招募、方案依从性、保留和随访、数据质量和研究启动时间，MFMU网络数据协调中心将我们在14个参与中心中排名第一。如果在这种竞争性的重新申请中取得成功，我们的设施，设备，数据管理系统（包括我们的电子围产期记录系统），招聘资源和众多训练有素的人员将继续利用MFMU网络协议和项目的服务。我们相信，在未来五年内，我们作为NICHD MFMU网络中心的竞争性更新仍然处于有利地位。

DESCRIPTION (provided by applicant): The Division of Maternal-Fetal Medicine at the University of Alabama at Birmingham (DAB) has a strong commitment to a continued high-level of participation in the NICHD MFMU Network for the purpose of investigating problems in clinical obstetrics, particularly those related to low birth weight, prematurity, and medical complications of pregnancy. We have extensive experience in performing clinical trials in these areas, and a strong, stable, and proven research infrastructure. We have been a participating center for the past three 5-year cycles of the MFMU Network. During that time, we have played a leadership role in providing research direction for the Network at the Steering and sub-committee levels, as a contributor to the conduct of Network trials, and in the presentation and publication of data generated by these trials. Nine different current UAB investigators have served or are serving as Network protocol chairmen or subcommittee members. One-third of Network publications have been first-authored by a UAB investigator, and of 95 total Network presentations at national meetings from 2002-2005, a UAB investigator presented 21. In the current 5-year cycle, on the basis of patient recruitment, protocol adherence, retention and follow-up, data quality, and study start-up time, the MFMU Network Data Coordinating Center ranked us #1 among the 14 participating centers. If successful in this competitive reapplication, our facilities, equipment, data management systems (including our electronic perinatal record system), recruitment resources, and numerous trained personnel will continue to be harnessed in the service of MFMU Network protocols and projects. We believe that we remain well positioned for competitive renewal as an NICHD MFMU Network center for the next five years.