Puerto Rico Drug Abuse Research Development Program (PRDARDP II)

描述（由申请人提供）：中加勒比大学（UCC）和位于波多黎各Bayamon的UCC医学院寻求对波多黎各药物滥用研究开发计划（PRDARP NIDA赠款编号5 R24 DA 13335）的持续支持，该计划以前曾在2000-2005年期间资助。这一竞争性申请旨在继续加强UCC医学院的药物使用研究基础设施，并培训六名新的研究人员和两名学生进入药物滥用和艾滋病毒/艾滋病研究界。根据我们成瘾研究中心和PRDARP研究人员以前的发现，这个新的应用程序将由压力-压力-应对模型指导。我们的新研究人员提出了三个项目，一个涉及压力及其介质的流行病学，一个研究药物使用和免疫系统压力的双重后果，第三个侧重于应对压力。所有这些都作为申请的一部分附在后面。拟议的培训课程包括多种教育战略，包括由高级导师和顾问进行个别辅导，举办关于艾滋病毒/艾滋病压力和抑郁症、研究方法和压力理论的年度讲习班。我们的目标是培训初级研究人员和学生，使他们继续寻找更好地了解波多黎各艾滋病毒/艾滋病流行病的方法，以便能够设计更有效的干预措施，制止该岛自我维持的流行病。

DESCRIPTION (provided by applicant): The Universidad del Central Caribe (UCC) and the UCC School of Medicine in Bayamon, Puerto Rico seeks continued support for the Puerto Rico Drug Abuse Research Development Program (PRDARP NIDA Grant No.5 R24 DA13335) previously funded for the years 2000-2005. This competing application seeks to continue the enhancement of the drug use research infrastructure at the UCC School of Medicine and to train six new researchers and two students to enter the drug abuse and HIV/AIDS research community. Based on previous findings by our Center of Addiction Studies and PRDARP researchers, this new application will be guided by the Stressors-Stress-Coping model. Three projects are proposed by our new investigators, one relating to the epidemiology of stress and its mediators, one examining the dual consequences of drug use and stress in the immune system, and the third focusing on coping with stress. All are enclosed as part of the application. The proposed training curriculum comprises multiple educational strategies including individual mentoring by senior mentors and consultants, yearly workshops related to HIV/AIDS stress and depression, research methodology, and the theory of stress. Our aim is to train junior researchers and students to continue searching for ways to better understand the HIV/AIDS epidemic in Puerto Rico so as to be able to design more effective interventions that will halt the island's self-sustaining epidemic.