Side effects of Cancer Therapy: Chemobrain: Mechanisms & Assessments

描述(申请人提供)：癌症治疗对正常组织的损伤是癌症患者经历的一个主要副作用，不幸的是，这是一个研究不足的领域。现在，仅在美国，癌症幸存者的数量就超过了1100万，而且全球的幸存者总数还在不断增加。肯塔基大学马基癌症中心关于癌症治疗的副作用：化疗：机制和评估的会议将于2011年10月12-14日在肯塔基州列克星敦举行，并将包括与癌症幸存者的开幕式。认知和记忆领域的两位著名科学家，加州大学圣地亚哥分校的拉里·斯奎尔和加州大学欧文分校的詹姆斯·麦高已经同意担任主旨演讲人。这次会议由Markey癌症中心主办，是一次国际研讨会，汇集了临床肿瘤学领域的科学家、医生、护士、保健专业人员、医生和受训科学家。会议的目标是协调、交流和传播信息，并探讨可能的干预措施。重点将集中在抗癌化疗药物不直接针对大脑导致神经元损伤的机制、评估策略、干预策略以及可能从基础研究转化为临床实践。 公共卫生相关性：癌症治疗引起的正常组织损伤是癌症患者经历的主要副作用，也是一个研究不足的领域。仅在美国，癌症幸存者的数量就超过了1100万人。因此，需要提供支持癌症治疗后高质量生活的医疗保健已成为新的医疗保健挑战，而非癌症组织的损伤需要特别关注。肯塔基大学马基癌症中心会议关于癌症治疗的副作用：化疗：机制和评估是一个非常及时和重要的主题，以造福患者。会议将于2011年10月12日至14日在肯塔基州列克星敦举行，并将包括与癌症幸存者的开幕式。这次会议是一次国际研讨会，汇集了癌症研究和化疗领域的临床医生和科学家社区。会议的目标是协调、交换和传播信息，探索新的策略来诊断和预防或最大限度地减少与不直接针对大脑的化疗药物相关的神经问题。

DESCRIPTION (provided by applicant): Cancer therapy-induced injury to normal tissue is a major side effect experienced by cancer patients and is, unfortunately, an understudied area. The number of cancer survivors now exceeds 11 million in the US alone and the total number of survivors worldwide is constantly increasing. The University of Kentucky Markey Cancer Center Conference on the Side Effects of Cancer Therapy:Chemobrain: Mechanisms & Assessments will be held in Lexington, Kentucky, during October 12-14, 2011, and will include an opening session with cancer survivors. Two prominent scientists in the area of cognition and memory, Larry Squire from UCSD and James McGaugh from UC Irvine, have agreed to be keynote speakers. The conference is sponsored by the Markey Cancer Center and is an international symposium bringing together a community of scientists, physicians, nurses, health care professionals, physicians and scientists-in-training in the area of clinical oncology. The objectives of the meeting are to coordinate, exchange, and disseminate information and to explore potential intervention. The focus will be the mechanisms of neuronal injury resulting from anticancer chemotherapeutic agents not directly targeting the brain, strategies for assessments, intervention strategies, and possible translation from basic studies into clinical practice. PUBLIC HEALTH RELEVANCE: Cancer therapy-induced normal tissue injury is a major side effect experienced by cancer patients and is an understudied area. The number of cancer survivors now exceeds 11 million in the US alone. As such, the need to provide health care that supports a high quality of life after cancer treatment has become a new health care challenge, and injury to noncancerous tissue is in need of special attention. The University of Kentucky Markey Cancer Center Conference on Side Effects of Cancer Therapy: Chemobrain: Mechanisms & Assessments is a very timely and important topic for the benefit of patients. The conference will be held in Lexington, Kentucky during October 12-14, 2011, and will include an opening session with cancer survivors. The conference is an international symposium bringing together a community of clinicians and scientists in the area of cancer research and chemotherapy. The goals of the conference are to coordinate, exchange, and disseminate information and to explore novel strategies to diagnose and to prevent or minimize the neurological problems associated with chemotherapeutic drugs not directly targeting the brain.