FASEB SRC on Nutritional Immunology: Its effects on health and disease.

描述(由申请者提供)：“营养免疫学：其对健康和疾病的影响”被FASEB选为2011年夏季研究会议，将于7月10日至15日在亚利桑那州的Carefree举行。这次会议围绕营养如何在改变肥胖、神经退行性疾病、哮喘、胃肠道疾病和传染病等疾病的免疫功能方面发挥作用的机制进行了组织。会议将包括关于尖端免疫学研究和技术的演讲，包括T细胞记忆、系统生物学方法、免疫细胞的代谢功能、下一代大规模并行测序和脂代谢。通过不仅将营养免疫学领域的工作人员聚集在一起，而且将免疫学和生物化学专家聚集在一起，我们可以开始开展多学科研究，以解决饮食调节人类健康的复杂问题。我们的第一个具体目标将是更好地了解宿主营养状况影响肥胖、糖尿病、衰老、炎症、胃肠道疾病、传染病和哮喘等疾病的机制。第二个具体目标是让参与者了解可应用于营养免疫学的其他领域的进展。最后，具体目标3是促进聚集在一起的研究人员小组内部的互动，以交流想法和专业知识，并制定合作项目。自2007年以来，营养免疫学没有举行过一次重大的全国会议，因此我们预计将有120-140人参加。 公共卫生相关性：本次会议具有很高的公共卫生相关性。了解宿主营养状况影响肥胖、胃肠道疾病、糖尿病、哮喘、传染病和神经退行性疾病等疾病的免疫反应的机制(S)，将有助于我们找到有助于预防/治疗这些疾病的营养免疫疗法。

DESCRIPTION (provided by applicant): "Nutritional Immunology: Its impact on Health and Disease" was selected by FASEB as a 2011 summer research conference to be held in Carefree, AZ, July 10-15. This meeting is organized around understanding mechanisms of how nutrition can play a role in altering the immune function in diseases such as obesity, neurodegeneration, asthma, gastrointestinal diseases and infectious disease. Sessions will include talks on cutting edge immunological research and techniques, including T cell memory, systems biology approaches, metabolic function of immune cells, next generation massively parallel sequencing, and lipodomics. By bringing together not only individuals working in the field of nutritional immunology, but also experts in immunology and biochemistry, we can begin to develop multidisciplinary studies to address complex issues of the modulation of human health by diet. Our first specific aim will be to better understand the mechanisms whereby host nutritional status can influence such diseases as obesity, diabetes, aging, inflammation, GI disorders, infectious disease, and asthma. The second specific aim is to expose participants to advances in other fields that can be applied to nutritional immunology. And finally, specific aim 3 is to promote interactions within the group of assembled investigators to develop an exchange of ideas and expertise and to develop collaborative projects, There has not been a major national meeting in nutritional immunology since 2007 and therefore we expect an attendance of 120-140 individuals. PUBLIC HEALTH RELEVANCE: This conference has high public health relevance. Understanding the mechanism(s) by which host nutritional status can influence the immune response in such diseases as obesity, GI disorders, diabetes, asthma, infectious diseases, and neurodegenerative diseases, will aid us in identifying nutritional immunotherapies that can help prevent/treat these diseases.