The First International Symposium on IgG4-Related Systemic Disease

简介(申请人提供)：我们计划组织和举办世界上第一个关于IgG4相关系统性疾病(IgG4-RSD)的国际研讨会。我们已经获得了世界主要研究人员的承诺，将参加这次研讨会。我们组委会的专业知识涵盖了目前关于IgG4-RSD的全部知识，包括内科、外科、病理学和放射科至少十几个子专科的专业知识，其中包括风湿病学、免疫学、变态反应、胃肠病理学、血管病理学、头颈病理学、断层影像(放射学)和肝胆外科。我们已经制定了一项议程，解决了当今该领域的研究人员和临床医生面临的主要问题，从围绕疾病发病机制的许多未知问题到疾病的临床谱。议程还将涵盖诊断标准、疾病活动指数的制定、关于标准治疗方法的协商一致讨论以及新的治疗方法。我们预计研讨会将出现几个新的方向，包括结果测量的验证研究，跨器官系统对疾病病理标准的更有针对性的讨论，数据和样本共享的计划，以及临床试验的发展。在存在新的治疗方法和对病理生理学的新见解的时候，拟议的研讨会将对世界上的IgG4-RSD研究人员产生激励作用。

DESCRIPTION (provided by applicant): We plan to organize and conduct the world's first international symposium on IgG4- related systemic disease (IgG4-RSD). We have secured commitments from the world's major researchers to participate in this Symposium. The expertise of our Organizing Committees spans the full spectrum of current knowledge about IgG4-RSD, and includes expertise from at least a dozen subspecialties within medicine, surgery, pathology, and radiology, among which are Rheumatology, Immunology, Allergy, Gastroenterology, Gastrointestinal Pathology, Vascular Pathology, Head & Neck Pathology, cross-sectional imaging (Radiology), and Hepatobiliary Surgery. We have developed an agenda that addresses the major questions confronting researchers and clinicians in the field today, from the many unknowns surrounding disease pathogenesis to the clinical spectrum of disease. The agenda will also cover diagnostic criteria, the development of disease activity indices, consensus discussions on standard approaches to therapy, and novel treatments. We anticipate several new directions emerging from the Symposium, including validation studies for outcome measures, more directed discussions about pathologic criteria for the disease across organ systems, plans for data and sample sharing, and the development of clinical trials. The proposed Symposium will have a galvanizing effect on the world's IgG4-RSD investigators at a time when the possibility of novel treatment approaches and new insights into pathophysiology exist.